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Discovery of novel benzoquinazolinones and thiazoloimidazoles, inhibitors of influenza H5N1 and H1N1 viruses, from a cell-based high-throughput screen.
Maddry JA, Chen X, Jonsson CB, Ananthan S, Hobrath J, Smee DF, Noah JW, Noah D, Xu X, Jia F, Maddox C, Sosa MI, White EL, Severson WE. Maddry JA, et al. Among authors: jonsson cb. J Biomol Screen. 2011 Jan;16(1):73-81. doi: 10.1177/1087057110384613. Epub 2010 Nov 8. J Biomol Screen. 2011. PMID: 21059874 Free PMC article.
(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection.
Moore BP, Chung DH, Matharu DS, Golden JE, Maddox C, Rasmussen L, Noah JW, Sosa MI, Ananthan S, Tower NA, White EL, Jia F, Prisinzano TE, Aubé J, Jonsson CB, Severson WE. Moore BP, et al. Among authors: jonsson cb. J Med Chem. 2012 Oct 25;55(20):8582-7. doi: 10.1021/jm300612z. Epub 2012 Oct 16. J Med Chem. 2012. PMID: 23043370 Free PMC article.
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA. Chung DH, et al. Among authors: jonsson cb. PLoS Pathog. 2014 Jun 26;10(6):e1004213. doi: 10.1371/journal.ppat.1004213. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24967809 Free PMC article.
Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity.
Matharu DS, Flaherty DP, Simpson DS, Schroeder CE, Chung D, Yan D, Noah JW, Jonsson CB, White EL, Aubé J, Plemper RK, Severson WE, Golden JE. Matharu DS, et al. Among authors: jonsson cb. J Med Chem. 2014 Dec 26;57(24):10314-28. doi: 10.1021/jm500902x. Epub 2014 Dec 4. J Med Chem. 2014. PMID: 25399509 Free PMC article.
153 results