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A high-throughput screening strategy to overcome virus instability.
Rasmussen L, Maddox C, Moore BP, Severson W, White EL. Rasmussen L, et al. Among authors: white el. Assay Drug Dev Technol. 2011 Apr;9(2):184-90. doi: 10.1089/adt.2010.0298. Epub 2010 Nov 4. Assay Drug Dev Technol. 2011. PMID: 21050067 Free PMC article.
Discovery of novel benzoquinazolinones and thiazoloimidazoles, inhibitors of influenza H5N1 and H1N1 viruses, from a cell-based high-throughput screen.
Maddry JA, Chen X, Jonsson CB, Ananthan S, Hobrath J, Smee DF, Noah JW, Noah D, Xu X, Jia F, Maddox C, Sosa MI, White EL, Severson WE. Maddry JA, et al. Among authors: white el. J Biomol Screen. 2011 Jan;16(1):73-81. doi: 10.1177/1087057110384613. Epub 2010 Nov 8. J Biomol Screen. 2011. PMID: 21059874 Free PMC article.
Screening methods for influenza antiviral drug discovery.
Atkins C, Evans CW, White EL, Noah JW. Atkins C, et al. Among authors: white el. Expert Opin Drug Discov. 2012 May;7(5):429-38. doi: 10.1517/17460441.2012.674510. Epub 2012 Mar 22. Expert Opin Drug Discov. 2012. PMID: 22435452 Review.
(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection.
Moore BP, Chung DH, Matharu DS, Golden JE, Maddox C, Rasmussen L, Noah JW, Sosa MI, Ananthan S, Tower NA, White EL, Jia F, Prisinzano TE, Aubé J, Jonsson CB, Severson WE. Moore BP, et al. Among authors: white el. J Med Chem. 2012 Oct 25;55(20):8582-7. doi: 10.1021/jm300612z. Epub 2012 Oct 16. J Med Chem. 2012. PMID: 23043370 Free PMC article.
209 results