Tham LS - Search Results

1

Pharmacogenetics of SLCO1B1 gene and the impact of *1b and *15 haplotypes on irinotecan disposition in Asian cancer patients.

Xiang X, Jada SR, Li HH, Fan L, Tham LS, Wong CI, Lee SC, Lim R, Zhou QY, Goh BC, Tan EH, Chowbay B. Xiang X, et al. Among authors: tham ls. Pharmacogenet Genomics. 2006 Sep;16(9):683-91. doi: 10.1097/01.fpc.0000230420.05221.71. Pharmacogenet Genomics. 2006. PMID: 16906022 Clinical Trial.

2

Population pharmacokinetics of tacrolimus in whole blood and plasma in asian liver transplant patients.

Sam WJ, Tham LS, Holmes MJ, Aw M, Quak SH, Lee KH, Lim SG, Prabhakaran K, Chan SY, Ho PC. Sam WJ, et al. Among authors: tham ls. Clin Pharmacokinet. 2006;45(1):59-75. doi: 10.2165/00003088-200645010-00004. Clin Pharmacokinet. 2006. PMID: 16430311

3

Ketoconazole renders poor CYP3A phenotype status with midazolam as probe drug.

Tham LS, Lee HS, Wang L, Yong WP, Fan L, Ong AB, Sukri N, Soo R, Lee SC, Goh BC. Tham LS, et al. Ther Drug Monit. 2006 Apr;28(2):255-61. doi: 10.1097/01.ftd.0000194497.55269.d9. Ther Drug Monit. 2006. PMID: 16628140 Clinical Trial.

4

A multicentre randomised phase II study of carboplatin in combination with gemcitabine at standard rate or fixed dose rate infusion in patients with advanced stage non-small-cell lung cancer.

Soo RA, Wang LZ, Tham LS, Yong WP, Boyer M, Lim HL, Lee HS, Millward M, Liang S, Beale P, Lee SC, Goh BC. Soo RA, et al. Among authors: tham ls. Ann Oncol. 2006 Jul;17(7):1128-33. doi: 10.1093/annonc/mdl084. Epub 2006 May 2. Ann Oncol. 2006. PMID: 16670205 Free article. Clinical Trial.

5

Distribution of gemcitabine pathway genotypes in ethnic Asians and their association with outcome in non-small cell lung cancer patients.

Soo RA, Wang LZ, Ng SS, Chong PY, Yong WP, Lee SC, Liu JJ, Choo TB, Tham LS, Lee HS, Goh BC, Soong R. Soo RA, et al. Among authors: tham ls. Lung Cancer. 2009 Jan;63(1):121-7. doi: 10.1016/j.lungcan.2008.04.010. Epub 2008 Jun 5. Lung Cancer. 2009. PMID: 18538445

6

A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients.

Tham LS, Wang L, Soo RA, Lee SC, Lee HS, Yong WP, Goh BC, Holford NH. Tham LS, et al. Clin Cancer Res. 2008 Jul 1;14(13):4213-8. doi: 10.1158/1078-0432.CCR-07-4754. Clin Cancer Res. 2008. PMID: 18594002 Clinical Trial.

7

A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers.

Yong WP, Wang LZ, Tham LS, Wong CI, Lee SC, Soo R, Sukri N, Lee HS, Goh BC. Yong WP, et al. Among authors: tham ls. Cancer Chemother Pharmacol. 2008 Jul;62(2):243-51. doi: 10.1007/s00280-007-0598-1. Epub 2007 Oct 2. Cancer Chemother Pharmacol. 2008. PMID: 17909805 Clinical Trial.

8

Lack of association of single-nucleotide polymorphisms in pregnane X receptor, hepatic nuclear factor 4alpha, and constitutive androstane receptor with docetaxel pharmacokinetics.

Tham LS, Holford NH, Hor SY, Tan T, Wang L, Lim RC, Lee HS, Lee SC, Goh BC. Tham LS, et al. Clin Cancer Res. 2007 Dec 1;13(23):7126-32. doi: 10.1158/1078-0432.CCR-07-1276. Clin Cancer Res. 2007. PMID: 18056193 Clinical Trial.

9

Population exposure-response model to support dosing evaluation of ixekizumab in patients with chronic plaque psoriasis.

Tham LS, Tang CC, Choi SL, Satterwhite JH, Cameron GS, Banerjee S. Tham LS, et al. J Clin Pharmacol. 2014 Oct;54(10):1117-24. doi: 10.1002/jcph.312. Epub 2014 Apr 23. J Clin Pharmacol. 2014. PMID: 24752880 Clinical Trial.

10

Does saturable formation of gemcitabine triphosphate occur in patients?

Tham LS, Wang LZ, Soo RA, Lee HS, Lee SC, Goh BC, Holford NH. Tham LS, et al. Cancer Chemother Pharmacol. 2008 Dec;63(1):55-64. doi: 10.1007/s00280-008-0707-9. Epub 2008 Feb 28. Cancer Chemother Pharmacol. 2008. PMID: 18305939

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