Ding W - Search Results

1

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.

Tsao DH, Sutherland AG, Jennings LD, Li Y, Rush TS 3rd, Alvarez JC, Ding W, Dushin EG, Dushin RG, Haney SA, Kenny CH, Malakian AK, Nilakantan R, Mosyak L. Tsao DH, et al. Among authors: ding w. Bioorg Med Chem. 2006 Dec 1;14(23):7953-61. doi: 10.1016/j.bmc.2006.07.050. Epub 2006 Aug 17. Bioorg Med Chem. 2006. PMID: 16919463

2

Development of a fluorescence polarization assay to screen for inhibitors of the FtsZ/ZipA interaction.

Kenny CH, Ding W, Kelleher K, Benard S, Dushin EG, Sutherland AG, Mosyak L, Kriz R, Ellestad G. Kenny CH, et al. Among authors: ding w. Anal Biochem. 2003 Dec 15;323(2):224-33. doi: 10.1016/j.ab.2003.08.033. Anal Biochem. 2003. PMID: 14656529

3

Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction.

Sutherland AG, Alvarez J, Ding W, Foreman KW, Kenny CH, Labthavikul P, Mosyak L, Petersen PJ, Rush TS 3rd, Ruzin A, Tsao DH, Wheless KL. Sutherland AG, et al. Among authors: ding w. Org Biomol Chem. 2003 Dec 7;1(23):4138-40. doi: 10.1039/b312016c. Epub 2003 Oct 29. Org Biomol Chem. 2003. PMID: 14685315

4

Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.

Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG. Jennings LD, et al. Among authors: ding w. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31. doi: 10.1016/j.bmcl.2004.01.028. Bioorg Med Chem Lett. 2004. PMID: 15006376

5

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.

Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Kincaid SL, Sukhdeo MN, Sutherland AG, Ding W, Kenny CH, Sabus CL, Liu H, Dushin EG, Moghazeh SL, Labthavikul P, Petersen PJ, Tuckman M, Haney SA, Ruzin AV. Jennings LD, et al. Among authors: ding w. Bioorg Med Chem. 2004 Oct 1;12(19):5115-31. doi: 10.1016/j.bmc.2004.07.031. Bioorg Med Chem. 2004. PMID: 15351395

6

Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine.

Salaski EJ, Krishnamurthy G, Ding WD, Yu K, Insaf SS, Eid C, Shim J, Levin JI, Tabei K, Toral-Barza L, Zhang WG, McDonald LA, Honores E, Hanna C, Yamashita A, Johnson B, Li Z, Laakso L, Powell D, Mansour TS. Salaski EJ, et al. J Med Chem. 2009 Apr 23;52(8):2181-4. doi: 10.1021/jm900075g. J Med Chem. 2009. PMID: 19309081

7

Novel and specific respiratory syncytial virus inhibitors that target virus fusion.

Ding WD, Mitsner B, Krishnamurthy G, Aulabaugh A, Hess CD, Zaccardi J, Cutler M, Feld B, Gazumyan A, Raifeld Y, Nikitenko A, Lang SA, Gluzman Y, O'Hara B, Ellestad GA. Ding WD, et al. J Med Chem. 1998 Jul 16;41(15):2671-5. doi: 10.1021/jm980239e. J Med Chem. 1998. PMID: 9667956 No abstract available.

8

Pyrimido[1,2-b]-1,2,4,5-tetrazin-6-ones as HCMV protease inhibitors: a new class of heterocycles with flavin-like redox properties.

Di Grandi MJ, Curran KJ, Baum EZ, Bebernitz G, Ellestad GA, Ding WD, Lang SA, Rossi M, Bloom JD. Di Grandi MJ, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3483-6. doi: 10.1016/s0960-894x(03)00789-3. Bioorg Med Chem Lett. 2003. PMID: 14505653

9

Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines.

Toral-Barza L, Zhang WG, Huang X, McDonald LA, Salaski EJ, Barbieri LR, Ding WD, Krishnamurthy G, Hu YB, Lucas J, Bernan VS, Cai P, Levin JI, Mansour TS, Gibbons JJ, Abraham RT, Yu K. Toral-Barza L, et al. Mol Cancer Ther. 2007 Nov;6(11):3028-38. doi: 10.1158/1535-7163.MCT-07-0211. Epub 2007 Nov 7. Mol Cancer Ther. 2007. PMID: 17989320

10

Theoretical simulation of the electronic circular dichroism spectrum of calicheamicin.

Giorgio E, Tanaka K, Ding W, Krishnamurthy G, Pitts K, Ellestad GA, Rosini C, Berova N. Giorgio E, et al. Among authors: ding w. Bioorg Med Chem. 2005 Sep 1;13(17):5072-9. doi: 10.1016/j.bmc.2005.04.007. Bioorg Med Chem. 2005. PMID: 16051103

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