Tortorella V - Search Results

1

Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents.

De Bellis M, De Luca A, Rana F, Cavalluzzi MM, Catalano A, Lentini G, Franchini C, Tortorella V, Conte Camerino D. De Bellis M, et al. Among authors: tortorella v. Br J Pharmacol. 2006 Oct;149(3):300-10. doi: 10.1038/sj.bjp.0706867. Epub 2006 Aug 21. Br J Pharmacol. 2006. PMID: 16921388 Free PMC article.

2

Stereospecific synthesis of "para-hydroxymexiletine" and sodium channel blocking activity evaluation.

Catalano A, Carocci A, Fracchiolla G, Franchini C, Lentini G, Tortorella V, De Luca A, De Bellis M, Desaphy JF, Conte Camerino D. Catalano A, et al. Among authors: tortorella v. Chirality. 2004 Feb;16(2):72-8. doi: 10.1002/chir.10307. Chirality. 2004. PMID: 14712469

3

Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.

Catalano A, Carocci A, Corbo F, Franchini C, Muraglia M, Scilimati A, De Bellis M, De Luca A, Camerino DC, Sinicropi MS, Tortorella V. Catalano A, et al. Among authors: tortorella v. Eur J Med Chem. 2008 Nov;43(11):2535-40. doi: 10.1016/j.ejmech.2008.01.023. Epub 2008 Jan 31. Eur J Med Chem. 2008. PMID: 18342401

4

Inhibition of skeletal muscle sodium currents by mexiletine analogues: specific hydrophobic interactions rather than lipophilia per se account for drug therapeutic profile.

De Luca A, Talon S, De Bellis M, Desaphy JF, Franchini C, Lentini G, Catalano A, Corbo F, Tortorella V, Conte-Camerino D. De Luca A, et al. Among authors: tortorella v. Naunyn Schmiedebergs Arch Pharmacol. 2003 Mar;367(3):318-27. doi: 10.1007/s00210-002-0669-0. Epub 2003 Jan 25. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12644906

5

Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.

De Luca A, Talon S, De Bellis M, Desaphy JF, Lentini G, Corbo F, Scilimati A, Franchini C, Tortorella V, Camerino DC. De Luca A, et al. Among authors: tortorella v. Mol Pharmacol. 2003 Oct;64(4):932-45. doi: 10.1124/mol.64.4.932. Mol Pharmacol. 2003. PMID: 14500750

6

Chloride channels of skeletal muscle from developing, adult and aged rats are differently affected by enantiomers of 2-(p-chlorophenoxy) propionic acid.

De Luca A, Tortorella V, Conte Camerino D. De Luca A, et al. Among authors: tortorella v. Naunyn Schmiedebergs Arch Pharmacol. 1992 Dec;346(6):601-6. doi: 10.1007/BF00168731. Naunyn Schmiedebergs Arch Pharmacol. 1992. PMID: 1336571

7

Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers.

De Luca A, Natuzzi F, Lentini G, Franchini C, Tortorella V, Conte Camerino D. De Luca A, et al. Among authors: tortorella v. Naunyn Schmiedebergs Arch Pharmacol. 1995 Dec;352(6):653-61. doi: 10.1007/BF00171325. Naunyn Schmiedebergs Arch Pharmacol. 1995. PMID: 9053738

8

Evaluation of the antimyotonic activity of mexiletine and some new analogs on sodium currents of single muscle fibers and on the abnormal excitability of the myotonic ADR mouse.

De Luca A, Pierno S, Natuzzi F, Franchini C, Duranti A, Lentini G, Tortorella V, Jockusch H, Camerino DC. De Luca A, et al. Among authors: tortorella v. J Pharmacol Exp Ther. 1997 Jul;282(1):93-100. J Pharmacol Exp Ther. 1997. PMID: 9223544

9

Inhibition of frog skeletal muscle sodium channels by newly synthesized chiral derivatives of mexiletine and tocainide.

De Luca A, Natuzzi F, Falcone G, Duranti A, Lentini G, Franchini C, Tortorella V, Camerino DC. De Luca A, et al. Among authors: tortorella v. Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):777-87. doi: 10.1007/pl00005118. Naunyn Schmiedebergs Arch Pharmacol. 1997. PMID: 9453464

10

Effects of mexiletine on ATP sensitive K+ channel of rat skeletal muscle fibres: a state dependent mechanism of action.

Tricarico D, Barbieri M, Franchini C, Tortorella V, Camerino DC. Tricarico D, et al. Among authors: tortorella v. Br J Pharmacol. 1998 Oct;125(4):858-64. doi: 10.1038/sj.bjp.0702117. Br J Pharmacol. 1998. PMID: 9831925 Free PMC article.

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