O'Garra A - Search Results

1

Critical role of type 1 cytokines in controlling initial infection with Burkholderia mallei.

Rowland CA, Lertmemongkolchai G, Bancroft A, Haque A, Lever MS, Griffin KF, Jackson MC, Nelson M, O'Garra A, Grencis R, Bancroft GJ, Lukaszewski RA. Rowland CA, et al. Infect Immun. 2006 Sep;74(9):5333-40. doi: 10.1128/IAI.02046-05. Infect Immun. 2006. PMID: 16926428 Free PMC article.

2

Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection.

Haque A, Easton A, Smith D, O'Garra A, Van Rooijen N, Lertmemongkolchai G, Titball RW, Bancroft GJ. Haque A, et al. J Infect Dis. 2006 Feb 1;193(3):370-9. doi: 10.1086/498983. Epub 2005 Dec 27. J Infect Dis. 2006. PMID: 16388484

3

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages.

Howes A, Taubert C, Blankley S, Spink N, Wu X, Graham CM, Zhao J, Saraiva M, Ricciardi-Castagnoli P, Bancroft GJ, O'Garra A. Howes A, et al. J Immunol. 2016 Oct 1;197(7):2838-53. doi: 10.4049/jimmunol.1501923. Epub 2016 Aug 22. J Immunol. 2016. PMID: 27549173 Free PMC article.

4

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung.

Redford PS, Boonstra A, Read S, Pitt J, Graham C, Stavropoulos E, Bancroft GJ, O'Garra A. Redford PS, et al. Eur J Immunol. 2010 Aug;40(8):2200-10. doi: 10.1002/eji.201040433. Eur J Immunol. 2010. PMID: 20518032 Free PMC article.

5

Blockade of IL-10 signaling during bacillus Calmette-Guérin vaccination enhances and sustains Th1, Th17, and innate lymphoid IFN-γ and IL-17 responses and increases protection to Mycobacterium tuberculosis infection.

Pitt JM, Stavropoulos E, Redford PS, Beebe AM, Bancroft GJ, Young DB, O'Garra A. Pitt JM, et al. J Immunol. 2012 Oct 15;189(8):4079-87. doi: 10.4049/jimmunol.1201061. Epub 2012 Sep 12. J Immunol. 2012. PMID: 22972927 Free PMC article.

6

The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease.

Conejero L, Potempa K, Graham CM, Spink N, Blankley S, Salguero FJ, Pankla-Sranujit R, Khaenam P, Banchereau JF, Pascual V, Chaussabel D, Lertmemongkolchai G, O'Garra A, Bancroft GJ. Conejero L, et al. J Immunol. 2015 Oct 1;195(7):3248-3261. doi: 10.4049/jimmunol.1500641. Epub 2015 Aug 26. J Immunol. 2015. PMID: 26311902 Free PMC article.

7

Immunomodulatory role of endogenous interleukin-18 in gamma interferon-mediated resolution of replicative Legionella pneumophila lung infection.

Brieland JK, Jackson C, Hurst S, Loebenberg D, Muchamuel T, Debets R, Kastelein R, Churakova T, Abrams J, Hare R, O'Garra A. Brieland JK, et al. Infect Immun. 2000 Dec;68(12):6567-73. doi: 10.1128/IAI.68.12.6567-6573.2000. Infect Immun. 2000. PMID: 11083766 Free PMC article.

8

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.

9

Further checkpoints in Th1 development.

Robinson DS, O'Garra A. Robinson DS, et al. Immunity. 2002 Jun;16(6):755-8. doi: 10.1016/s1074-7613(02)00331-x. Immunity. 2002. PMID: 12121657 Free article. Review.

10

Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose.

Saraiva M, Christensen JR, Veldhoen M, Murphy TL, Murphy KM, O'Garra A. Saraiva M, et al. Immunity. 2009 Aug 21;31(2):209-19. doi: 10.1016/j.immuni.2009.05.012. Epub 2009 Jul 30. Immunity. 2009. PMID: 19646904 Free PMC article.

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