Linne U - Search Results

1

In vivo biocombinatorial synthesis of lipopeptides by COM domain-mediated reprogramming of the surfactin biosynthetic complex.

Chiocchini C, Linne U, Stachelhaus T. Chiocchini C, et al. Among authors: linne u. Chem Biol. 2006 Aug;13(8):899-908. doi: 10.1016/j.chembiol.2006.06.015. Chem Biol. 2006. PMID: 16931339

2

Control of directionality in nonribosomal peptide synthesis: role of the condensation domain in preventing misinitiation and timing of epimerization.

Linne U, Marahiel MA. Linne U, et al. Biochemistry. 2000 Aug 29;39(34):10439-47. doi: 10.1021/bi000768w. Biochemistry. 2000. PMID: 10956034

3

Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes.

Mootz HD, Kessler N, Linne U, Eppelmann K, Schwarzer D, Marahiel MA. Mootz HD, et al. Among authors: linne u. J Am Chem Soc. 2002 Sep 18;124(37):10980-1. doi: 10.1021/ja027276m. J Am Chem Soc. 2002. PMID: 12224936

4

Evidence for a monomeric structure of nonribosomal Peptide synthetases.

Sieber SA, Linne U, Hillson NJ, Roche E, Walsh CT, Marahiel MA. Sieber SA, et al. Among authors: linne u. Chem Biol. 2002 Sep;9(9):997-1008. doi: 10.1016/s1074-5521(02)00214-4. Chem Biol. 2002. PMID: 12323374

5

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

Schwarzer D, Mootz HD, Linne U, Marahiel MA. Schwarzer D, et al. Among authors: linne u. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14083-8. doi: 10.1073/pnas.212382199. Epub 2002 Oct 16. Proc Natl Acad Sci U S A. 2002. PMID: 12384573 Free PMC article.

6

Systematic and quantitative analysis of protein-protein recognition between nonribosomal peptide synthetases investigated in the tyrocidine biosynthetic template.

Linne U, Stein DB, Mootz HD, Marahiel MA. Linne U, et al. Biochemistry. 2003 May 6;42(17):5114-24. doi: 10.1021/bi034223o. Biochemistry. 2003. PMID: 12718555

7

The linear pentadecapeptide gramicidin is assembled by four multimodular nonribosomal peptide synthetases that comprise 16 modules with 56 catalytic domains.

Kessler N, Schuhmann H, Morneweg S, Linne U, Marahiel MA. Kessler N, et al. Among authors: linne u. J Biol Chem. 2004 Feb 27;279(9):7413-9. doi: 10.1074/jbc.M309658200. Epub 2003 Dec 11. J Biol Chem. 2004. PMID: 14670971 Free article.

8

Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics.

Grünewald J, Sieber SA, Mahlert C, Linne U, Marahiel MA. Grünewald J, et al. Among authors: linne u. J Am Chem Soc. 2004 Dec 29;126(51):17025-31. doi: 10.1021/ja045455t. J Am Chem Soc. 2004. PMID: 15612741

9

Fluorescence resonance energy transfer as a probe of peptide cyclization catalyzed by nonribosomal thioesterase domains.

Grünewald J, Kopp F, Mahlert C, Linne U, Sieber SA, Marahiel MA. Grünewald J, et al. Among authors: linne u. Chem Biol. 2005 Aug;12(8):873-81. doi: 10.1016/j.chembiol.2005.05.019. Chem Biol. 2005. PMID: 16125099

10

Impact of epimerization domains on the intermodular transfer of enzyme-bound intermediates in nonribosomal peptide synthesis.

Stein DB, Linne U, Hahn M, Marahiel MA. Stein DB, et al. Among authors: linne u. Chembiochem. 2006 Nov;7(11):1807-14. doi: 10.1002/cbic.200600192. Chembiochem. 2006. PMID: 16952189

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