Stachelhaus T - Search Results

1

In vivo biocombinatorial synthesis of lipopeptides by COM domain-mediated reprogramming of the surfactin biosynthetic complex.

Chiocchini C, Linne U, Stachelhaus T. Chiocchini C, et al. Among authors: stachelhaus t. Chem Biol. 2006 Aug;13(8):899-908. doi: 10.1016/j.chembiol.2006.06.015. Chem Biol. 2006. PMID: 16931339

2

Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides.

Hahn M, Stachelhaus T. Hahn M, et al. Among authors: stachelhaus t. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):275-80. doi: 10.1073/pnas.0508409103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407157 Free PMC article.

3

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases.

Stachelhaus T, Mootz HD, Marahiel MA. Stachelhaus T, et al. Chem Biol. 1999 Aug;6(8):493-505. doi: 10.1016/S1074-5521(99)80082-9. Chem Biol. 1999. PMID: 10421756

4

Biochemical characterization of peptidyl carrier protein (PCP), the thiolation domain of multifunctional peptide synthetases.

Stachelhaus T, Hüser A, Marahiel MA. Stachelhaus T, et al. Chem Biol. 1996 Nov;3(11):913-21. doi: 10.1016/s1074-5521(96)90180-5. Chem Biol. 1996. PMID: 8939706

5

Aminoacyl-SNACs as small-molecule substrates for the condensation domains of nonribosomal peptide synthetases.

Ehmann DE, Trauger JW, Stachelhaus T, Walsh CT. Ehmann DE, et al. Among authors: stachelhaus t. Chem Biol. 2000 Oct;7(10):765-72. doi: 10.1016/s1074-5521(00)00022-3. Chem Biol. 2000. PMID: 11033080

6

Selective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains.

Hahn M, Stachelhaus T. Hahn M, et al. Among authors: stachelhaus t. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15585-90. doi: 10.1073/pnas.0404932101. Epub 2004 Oct 21. Proc Natl Acad Sci U S A. 2004. PMID: 15498872 Free PMC article.

7

Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the condensation domain.

Stachelhaus T, Mootz HD, Bergendahl V, Marahiel MA. Stachelhaus T, et al. J Biol Chem. 1998 Aug 28;273(35):22773-81. doi: 10.1074/jbc.273.35.22773. J Biol Chem. 1998. PMID: 9712910 Free article.

8

Exploitation of the selectivity-conferring code of nonribosomal peptide synthetases for the rational design of novel peptide antibiotics.

Eppelmann K, Stachelhaus T, Marahiel MA. Eppelmann K, et al. Among authors: stachelhaus t. Biochemistry. 2002 Jul 30;41(30):9718-26. doi: 10.1021/bi0259406. Biochemistry. 2002. PMID: 12135394

9

Rational design of peptide antibiotics by targeted replacement of bacterial and fungal domains.

Stachelhaus T, Schneider A, Marahiel MA. Stachelhaus T, et al. Science. 1995 Jul 7;269(5220):69-72. doi: 10.1126/science.7604280. Science. 1995. PMID: 7604280

10

Targeted alteration of the substrate specificity of peptide synthetases by rational module swapping.

Schneider A, Stachelhaus T, Marahiel MA. Schneider A, et al. Among authors: stachelhaus t. Mol Gen Genet. 1998 Feb;257(3):308-18. doi: 10.1007/s004380050652. Mol Gen Genet. 1998. PMID: 9520265

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