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Page 1
The absorption, metabolism, and excretion of the novel neuromodulator RWJ-333369 (1,2-ethanediol, [1-2-chlorophenyl]-, 2-carbamate, [S]-) in humans.
Mannens GS, Hendrickx J, Janssen CG, Chien S, Van Hoof B, Verhaeghe T, Kao M, Kelley MF, Goris I, Bockx M, Verreet B, Bialer M, Meuldermans W. Mannens GS, et al. Among authors: goris i. Drug Metab Dispos. 2007 Apr;35(4):554-65. doi: 10.1124/dmd.106.011940. Epub 2006 Aug 25. Drug Metab Dispos. 2007. PMID: 16936066 Clinical Trial.
Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a farnesyl transferase inhibitor.
Garner RC, Goris I, Laenen AA, Vanhoutte E, Meuldermans W, Gregory S, Garner JV, Leong D, Whattam M, Calam A, Snel CA. Garner RC, et al. Among authors: goris i. Drug Metab Dispos. 2002 Jul;30(7):823-30. doi: 10.1124/dmd.30.7.823. Drug Metab Dispos. 2002. PMID: 12065441
Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib.
De Zwart L, Snoeys J, Jacobs F, Li LY, Poggesi I, Verboven P, Goris I, Scheers E, Wynant I, Monshouwer M, Mamidi RNVS. De Zwart L, et al. Among authors: goris i. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):1107-1118. doi: 10.1002/psp4.12682. Epub 2021 Aug 11. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34273250 Free PMC article.
Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice.
Stroobants S, Van Acker NG, Verheijen FW, Goris I, Daneels GF, Schot R, Verbeek E, Knaapen MW, De Bondt A, Göhlmann HW, Crauwels ML, Mancini GM, Andries LJ, Moechars DW, D'Hooge R. Stroobants S, et al. Among authors: goris i. Exp Neurol. 2017 May;291:106-119. doi: 10.1016/j.expneurol.2017.02.009. Epub 2017 Feb 9. Exp Neurol. 2017. PMID: 28189729 Free article.
JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity.
Arts J, King P, Mariën A, Floren W, Beliën A, Janssen L, Pilatte I, Roux B, Decrane L, Gilissen R, Hickson I, Vreys V, Cox E, Bol K, Talloen W, Goris I, Andries L, Du Jardin M, Janicot M, Page M, van Emelen K, Angibaud P. Arts J, et al. Among authors: goris i. Clin Cancer Res. 2009 Nov 15;15(22):6841-51. doi: 10.1158/1078-0432.CCR-09-0547. Epub 2009 Oct 27. Clin Cancer Res. 2009. PMID: 19861438
IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity.
Cryns K, Shamir A, Van Acker N, Levi I, Daneels G, Goris I, Bouwknecht JA, Andries L, Kass S, Agam G, Belmaker H, Bersudsky Y, Steckler T, Moechars D. Cryns K, et al. Among authors: goris i. Neuropsychopharmacology. 2008 Feb;33(3):674-84. doi: 10.1038/sj.npp.1301431. Epub 2007 Apr 25. Neuropsychopharmacology. 2008. PMID: 17460611
15 results