Schofield CJ - Search Results

1

Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.

Ehrismann D, Flashman E, Genn DN, Mathioudakis N, Hewitson KS, Ratcliffe PJ, Schofield CJ. Ehrismann D, et al. Among authors: schofield cj. Biochem J. 2007 Jan 1;401(1):227-34. doi: 10.1042/BJ20061151. Biochem J. 2007. PMID: 16952279 Free PMC article.

2

Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli.

Zhang Z, Schofield CJ, Baldwin JE, Thomas P, John P. Zhang Z, et al. Among authors: schofield cj. Biochem J. 1995 Apr 1;307 ( Pt 1)(Pt 1):77-85. doi: 10.1042/bj3070077. Biochem J. 1995. PMID: 7717997 Free PMC article.

3

Substrate specificity of L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase from Cephalosporium acremonium: demonstration of the structure of several unnatural tripeptide products.

Baldwin JE, Shiau CY, Byford MF, Schofield CJ. Baldwin JE, et al. Among authors: schofield cj. Biochem J. 1994 Jul 15;301 ( Pt 2)(Pt 2):367-72. doi: 10.1042/bj3010367. Biochem J. 1994. PMID: 8042979 Free PMC article.

4

Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis.

Lawrence CC, Sobey WJ, Field RA, Baldwin JE, Schofield CJ. Lawrence CC, et al. Among authors: schofield cj. Biochem J. 1996 Jan 1;313 ( Pt 1)(Pt 1):185-91. doi: 10.1042/bj3130185. Biochem J. 1996. PMID: 8546682 Free PMC article.

5

'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes.

Wright PA, Wilmouth RC, Clifton IJ, Schofield CJ. Wright PA, et al. Among authors: schofield cj. Biochem J. 2000 Oct 15;351 Pt 2(Pt 2):335-40. Biochem J. 2000. PMID: 11023818 Free PMC article.

6

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Jaakkola P, et al. Among authors: schofield cj. Science. 2001 Apr 20;292(5516):468-72. doi: 10.1126/science.1059796. Epub 2001 Apr 5. Science. 2001. PMID: 11292861

7

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ. Epstein AC, et al. Among authors: schofield cj. Cell. 2001 Oct 5;107(1):43-54. doi: 10.1016/s0092-8674(01)00507-4. Cell. 2001. PMID: 11595184 Free article.

8

Enzymatic synthesis of monocyclic beta-lactams.

Sleeman MC, MacKinnon CH, Hewitson KS, Schofield CJ. Sleeman MC, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2002 Feb 25;12(4):597-9. doi: 10.1016/s0960-894x(01)00806-x. Bioorg Med Chem Lett. 2002. PMID: 11844680

9

ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity.

Kershaw NJ, McNaughton HJ, Hewitson KS, Hernández H, Griffin J, Hughes C, Greaves P, Barton B, Robinson CV, Schofield CJ. Kershaw NJ, et al. Among authors: schofield cj. Eur J Biochem. 2002 Apr;269(8):2052-9. doi: 10.1046/j.1432-1033.2002.02853.x. Eur J Biochem. 2002. PMID: 11985581 Free article.

10

Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

Elkins JM, Clifton IJ, Hernández H, Doan LX, Robinson CV, Schofield CJ, Hewitson KS. Elkins JM, et al. Among authors: schofield cj. Biochem J. 2002 Sep 1;366(Pt 2):423-34. doi: 10.1042/BJ20020125. Biochem J. 2002. PMID: 12020346 Free PMC article.

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