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Molecular characterization of macbecin as an Hsp90 inhibitor.
Martin CJ, Gaisser S, Challis IR, Carletti I, Wilkinson B, Gregory M, Prodromou C, Roe SM, Pearl LH, Boyd SM, Zhang MQ. Martin CJ, et al. Among authors: zhang mq. J Med Chem. 2008 May 8;51(9):2853-7. doi: 10.1021/jm701558c. Epub 2008 Mar 22. J Med Chem. 2008. PMID: 18357975
Drug discovery beyond the 'rule-of-five'.
Zhang MQ, Wilkinson B. Zhang MQ, et al. Curr Opin Biotechnol. 2007 Dec;18(6):478-88. doi: 10.1016/j.copbio.2007.10.005. Epub 2007 Nov 26. Curr Opin Biotechnol. 2007. PMID: 18035532 Review.
Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.
Gregory MA, Bobardt M, Obeid S, Chatterji U, Coates NJ, Foster T, Gallay P, Leyssen P, Moss SJ, Neyts J, Nur-e-Alam M, Paeshuyse J, Piraee M, Suthar D, Warneck T, Zhang MQ, Wilkinson B. Gregory MA, et al. Among authors: zhang mq. Antimicrob Agents Chemother. 2011 May;55(5):1975-81. doi: 10.1128/AAC.01627-10. Epub 2011 Mar 7. Antimicrob Agents Chemother. 2011. PMID: 21383094 Free PMC article.
Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.
Woolard J, Vousden W, Moss SJ, Krishnakumar A, Gammons MV, Nowak DG, Dixon N, Micklefield J, Spannhoff A, Bedford MT, Gregory MA, Martin CJ, Leadlay PF, Zhang MQ, Harper SJ, Bates DO, Wilkinson B. Woolard J, et al. Among authors: zhang mq. Chem Sci. 2011 Feb 1;2011(2):273-278. doi: 10.1039/C0SC00297F. Chem Sci. 2011. PMID: 22822423 Free PMC article.
Recombinant strains for the enhanced production of bioengineered rapalogs.
Kendrew SG, Petkovic H, Gaisser S, Ready SJ, Gregory MA, Coates NJ, Nur-E-Alam M, Warneck T, Suthar D, Foster TA, McDonald L, Schlingman G, Koehn FE, Skotnicki JS, Carter GT, Moss SJ, Zhang MQ, Martin CJ, Sheridan RM, Wilkinson B. Kendrew SG, et al. Among authors: zhang mq. Metab Eng. 2013 Jan;15:167-73. doi: 10.1016/j.ymben.2012.11.001. Epub 2012 Nov 17. Metab Eng. 2013. PMID: 23164580
695 results