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Page 1
Utility of alkylaminoquinolinyl methanols as new antimalarial drugs.
Dow GS, Heady TN, Bhattacharjee AK, Caridha D, Gerena L, Gettayacamin M, Lanteri CA, Obaldia N 3rd, Roncal N, Shearer T, Smith PL, Tungtaeng A, Wolf L, Cabezas M, Yourick D, Smith KS. Dow GS, et al. Among authors: lanteri ca. Antimicrob Agents Chemother. 2006 Dec;50(12):4132-43. doi: 10.1128/AAC.00631-06. Epub 2006 Sep 11. Antimicrob Agents Chemother. 2006. PMID: 16966402 Free PMC article.
Structure-activity relationships amongst 4-position quinoline methanol antimalarials that inhibit the growth of drug sensitive and resistant strains of Plasmodium falciparum.
Milner E, McCalmont W, Bhonsle J, Caridha D, Carroll D, Gardner S, Gerena L, Gettayacamin M, Lanteri C, Luong T, Melendez V, Moon J, Roncal N, Sousa J, Tungtaeng A, Wipf P, Dow G. Milner E, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1347-51. doi: 10.1016/j.bmcl.2010.01.001. Epub 2010 Jan 7. Bioorg Med Chem Lett. 2010. PMID: 20097070
Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice.
Dow GS, Milner E, Bathurst I, Bhonsle J, Caridha D, Gardner S, Gerena L, Kozar M, Lanteri C, Mannila A, McCalmont W, Moon J, Read KD, Norval S, Roncal N, Shackleford DM, Sousa J, Steuten J, White KL, Zeng Q, Charman SA. Dow GS, et al. Malar J. 2011 Jun 6;10:150. doi: 10.1186/1475-2875-10-150. Malar J. 2011. PMID: 21645370 Free PMC article.
Measurements of 5,6-Orthoquinone, a Surrogate for the Presumed Active Primaquine Metabolite 5-Hydroxyprimaquine, in the Urine of Cambodian Adults.
Vanachayangkul P, Sea D, Wojnarski M, Sok S, Kodchakorn C, Ta-Aksorn W, Hom S, Ittiverakul M, Kuntawunginn W, Arsanok M, Buathong N, Heng TK, Nareth K, Nou S, Chandara S, Ly S, Oung P, Vesely B, Bennett J, Reichard G, Pybus B, Lanteri C, Saunders D, Fukuda M, Smith P, Dysoley L, Rekol H, Waters NC, Spring M. Vanachayangkul P, et al. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0182121. doi: 10.1128/AAC.01821-21. Epub 2022 Jan 3. Antimicrob Agents Chemother. 2022. PMID: 34978892 Free PMC article.
Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta).
Saunders D, Vanachayangkul P, Imerbsin R, Khemawoot P, Siripokasupkul R, Tekwani BL, Sampath A, Nanayakkara NP, Ohrt C, Lanteri C, Gettyacamin M, Teja-Isavadharm P, Walker L. Saunders D, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7283-91. doi: 10.1128/AAC.02576-13. Epub 2014 Sep 29. Antimicrob Agents Chemother. 2014. PMID: 25267666 Free PMC article.
Piperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia.
Vanachayangkul P, Lon C, Spring M, Sok S, Ta-Aksorn W, Kodchakorn C, Pann ST, Chann S, Ittiverakul M, Sriwichai S, Buathong N, Kuntawunginn W, So M, Youdaline T, Milner E, Wojnarski M, Lanteri C, Manning J, Prom S, Haigney M, Cantilena L, Saunders D. Vanachayangkul P, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02000-16. doi: 10.1128/AAC.02000-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28193647 Free PMC article. Clinical Trial.
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
Chaorattanakawee S, Saunders DL, Sea D, Chanarat N, Yingyuen K, Sundrakes S, Saingam P, Buathong N, Sriwichai S, Chann S, Se Y, Yom Y, Heng TK, Kong N, Kuntawunginn W, Tangthongchaiwiriya K, Jacob C, Takala-Harrison S, Plowe C, Lin JT, Chuor CM, Prom S, Tyner SD, Gosi P, Teja-Isavadharm P, Lon C, Lanteri CA. Chaorattanakawee S, et al. Among authors: lanteri ca. Antimicrob Agents Chemother. 2015 Aug;59(8):4631-43. doi: 10.1128/AAC.00366-15. Epub 2015 May 26. Antimicrob Agents Chemother. 2015. PMID: 26014942 Free PMC article.
Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand.
Boonyalai N, Thamnurak C, Sai-Ngam P, Ta-Aksorn W, Arsanok M, Uthaimongkol N, Sundrakes S, Chattrakarn S, Chaisatit C, Praditpol C, Fagnark W, Kirativanich K, Chaorattanakawee S, Vanachayangkul P, Lertsethtakarn P, Gosi P, Utainnam D, Rodkvamtook W, Kuntawunginn W, Vesely BA, Spring MD, Fukuda MM, Lanteri C, Walsh D, Saunders DL, Smith PL, Wojnarski M, Sirisopana N, Waters NC, Jongsakul K, Gaywee J. Boonyalai N, et al. Sci Rep. 2021 Jun 28;11(1):13419. doi: 10.1038/s41598-021-92735-6. Sci Rep. 2021. PMID: 34183715 Free PMC article.
44 results