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Overexpressed TP73 induces apoptosis in medulloblastoma.
Castellino RC, De Bortoli M, Lin LL, Skapura DG, Rajan JA, Adesina AM, Perlaky L, Irwin MS, Kim JY. Castellino RC, et al. BMC Cancer. 2007 Jul 12;7:127. doi: 10.1186/1471-2407-7-127. BMC Cancer. 2007. PMID: 17626635 Free PMC article.
Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D.
Castellino RC, De Bortoli M, Lu X, Moon SH, Nguyen TA, Shepard MA, Rao PH, Donehower LA, Kim JY. Castellino RC, et al. J Neurooncol. 2008 Feb;86(3):245-56. doi: 10.1007/s11060-007-9470-8. Epub 2007 Oct 12. J Neurooncol. 2008. PMID: 17932621 Free PMC article.
HDM2 promotes WIP1-mediated medulloblastoma growth.
Buss MC, Read TA, Schniederjan MJ, Gandhi K, Castellino RC. Buss MC, et al. Among authors: castellino rc. Neuro Oncol. 2012 Apr;14(4):440-58. doi: 10.1093/neuonc/nos001. Epub 2012 Feb 29. Neuro Oncol. 2012. PMID: 22379189 Free PMC article.
The rationale for targeted therapies in medulloblastoma.
MacDonald TJ, Aguilera D, Castellino RC. MacDonald TJ, et al. Among authors: castellino rc. Neuro Oncol. 2014 Jan;16(1):9-20. doi: 10.1093/neuonc/not147. Epub 2013 Dec 4. Neuro Oncol. 2014. PMID: 24305711 Free PMC article. Review.
41 results