Kruczynski A - Search Results

1

Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development.

Kruczynski A, Poli M, Dossi R, Chazottes E, Berrichon G, Ricome C, Giavazzi R, Hill BT, Taraboletti G. Kruczynski A, et al. Eur J Cancer. 2006 Nov;42(16):2821-32. doi: 10.1016/j.ejca.2006.06.019. Epub 2006 Sep 14. Eur J Cancer. 2006. PMID: 16973349

2

Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts.

Hill BT, Fiebig HH, Waud WR, Poupon MF, Colpaert F, Kruczynski A. Hill BT, et al. Among authors: kruczynski a. Eur J Cancer. 1999 Mar;35(3):512-20. doi: 10.1016/s0959-8049(98)00416-x. Eur J Cancer. 1999. PMID: 10448309

3

Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties.

Kruczynski A, Hill BT. Kruczynski A, et al. Crit Rev Oncol Hematol. 2001 Nov;40(2):159-73. doi: 10.1016/s1040-8428(01)00183-4. Crit Rev Oncol Hematol. 2001. PMID: 11682323 Review.

4

Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated Vinca alkaloid.

Kruczynski A, Barret JM, Etiévant C, Colpaert F, Fahy J, Hill BT. Kruczynski A, et al. Biochem Pharmacol. 1998 Mar 1;55(5):635-48. doi: 10.1016/s0006-2952(97)00505-4. Biochem Pharmacol. 1998. PMID: 9515574

5

Preclinical in vivo antitumor activity of vinflunine, a novel fluorinated Vinca alkaloid.

Kruczynski A, Colpaert F, Tarayre JP, Mouillard P, Fahy J, Hill BT. Kruczynski A, et al. Cancer Chemother Pharmacol. 1998;41(6):437-47. doi: 10.1007/s002800050764. Cancer Chemother Pharmacol. 1998. PMID: 9554586

6

Vinflunine (20',20'-difluoro-3',4'-dihydrovinorelbine), a novel Vinca alkaloid, which participates in P-glycoprotein (Pgp)-mediated multidrug resistance in vivo and in vitro.

Etievant C, Barret JM, Kruczynski A, Perrin D, Hill BT. Etievant C, et al. Among authors: kruczynski a. Invest New Drugs. 1998;16(1):3-17. doi: 10.1023/a:1006022811895. Invest New Drugs. 1998. PMID: 9740539

7

Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells.

Jean-Decoster C, Brichese L, Barret JM, Tollon Y, Kruczynski A, Hill BT, Wright M. Jean-Decoster C, et al. Among authors: kruczynski a. Anticancer Drugs. 1999 Jul;10(6):537-43. Anticancer Drugs. 1999. PMID: 10885901

8

Markedly diminished drug resistance-inducing properties of vinflunine (20',20'-difluoro-3',4'-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro.

Etiévant C, Kruczynski A, Barret JM, Tait AS, Kavallaris M, Hill BT. Etiévant C, et al. Among authors: kruczynski a. Cancer Chemother Pharmacol. 2001 Jul;48(1):62-70. doi: 10.1007/s002800100275. Cancer Chemother Pharmacol. 2001. PMID: 11488526

9

Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development.

Kruczynski A, Etiévant C, Perrin D, Chansard N, Duflos A, Hill BT. Kruczynski A, et al. Br J Cancer. 2002 Jan 7;86(1):143-50. doi: 10.1038/sj.bjc.6600025. Br J Cancer. 2002. PMID: 11857026 Free PMC article.

10

In vivo antitumor activity of F 11782, a non-intercalating dual catalytic inhibitor of topoisomerases I and II, against a panel of human tumor xenografts.

Kruczynski A, Ricome C, Waud WR, Hill BT. Kruczynski A, et al. J Exp Ther Oncol. 2002 Jul-Aug;2(4):219-27. doi: 10.1046/j.1359-4117.2002.01037.x. J Exp Ther Oncol. 2002. PMID: 12416026

The marked in vivo antitumor activity of F 11782 against murine experimental tumors (Kruczynski et al., Br J Cancer 83: 1516-24, 2000) has now been confirmed in a panel of human tumor xenografts. ...In contrast, no real activity was recorded against NCI-H460 (non sm …

The marked in vivo antitumor activity of F 11782 against murine experimental tumors (Kruczynski et al., Br J Cancer 83: 1516-24, 2000 …

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