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Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1.
Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Murray F, et al. Among authors: insel pa. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L294-303. doi: 10.1152/ajplung.00190.2006. Epub 2006 Sep 15. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 16980375 Free article.
Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry.
Zhang S, Patel HH, Murray F, Remillard CV, Schach C, Thistlethwaite PA, Insel PA, Yuan JX. Zhang S, et al. Among authors: insel pa. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1202-10. doi: 10.1152/ajplung.00214.2006. Epub 2006 Dec 22. Am J Physiol Lung Cell Mol Physiol. 2007. PMID: 17189322 Free article.
Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.
Patel HH, Zhang S, Murray F, Suda RY, Head BP, Yokoyama U, Swaney JS, Niesman IR, Schermuly RT, Pullamsetti SS, Thistlethwaite PA, Miyanohara A, Farquhar MG, Yuan JX, Insel PA. Patel HH, et al. Among authors: insel pa. FASEB J. 2007 Sep;21(11):2970-9. doi: 10.1096/fj.07-8424com. Epub 2007 Apr 30. FASEB J. 2007. PMID: 17470567
Regulation of pulmonary vasoconstriction by agonists and caveolae.
Schach C, Firth AL, Xu M, Remillard CV, Patel HH, Insel PA, Yuan JX. Schach C, et al. Among authors: insel pa. Exp Lung Res. 2008 May;34(4):195-208. doi: 10.1080/01902140801925471. Exp Lung Res. 2008. PMID: 18432456 Free PMC article.
Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling.
Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. Horikawa YT, et al. Among authors: insel pa. J Am Coll Cardiol. 2011 May 31;57(22):2273-83. doi: 10.1016/j.jacc.2010.12.032. J Am Coll Cardiol. 2011. PMID: 21616289 Free PMC article.
439 results