Hedley DW - Search Results

1

Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen.

Yip KW, Mao X, Au PY, Hedley DW, Chow S, Dalili S, Mocanu JD, Bastianutto C, Schimmer A, Liu FF. Yip KW, et al. Among authors: hedley dw. Clin Cancer Res. 2006 Sep 15;12(18):5557-69. doi: 10.1158/1078-0432.CCR-06-0536. Clin Cancer Res. 2006. PMID: 17000693

2

Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent.

Yip KW, Ito E, Mao X, Au PY, Hedley DW, Mocanu JD, Bastianutto C, Schimmer A, Liu FF. Yip KW, et al. Among authors: hedley dw. Mol Cancer Ther. 2006 Sep;5(9):2234-40. doi: 10.1158/1535-7163.MCT-06-0134. Mol Cancer Ther. 2006. PMID: 16985057

3

Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer.

Ito E, Yip KW, Katz D, Fonseca SB, Hedley DW, Chow S, Xu GW, Wood TE, Bastianutto C, Schimmer AD, Kelley SO, Liu FF. Ito E, et al. Among authors: hedley dw. Mol Pharmacol. 2009 Nov;76(5):969-83. doi: 10.1124/mol.109.055277. Epub 2009 Aug 4. Mol Pharmacol. 2009. PMID: 19654225

4

The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.

Pham NA, Jacobberger JW, Schimmer AD, Cao P, Gronda M, Hedley DW. Pham NA, et al. Among authors: hedley dw. Mol Cancer Ther. 2004 Oct;3(10):1239-48. Mol Cancer Ther. 2004. PMID: 15486191

5

Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acid.

Gurfinkel DM, Chow S, Hurren R, Gronda M, Henderson C, Berube C, Hedley DW, Schimmer AD. Gurfinkel DM, et al. Among authors: hedley dw. Apoptosis. 2006 Sep;11(9):1463-71. doi: 10.1007/s10495-006-9086-z. Apoptosis. 2006. PMID: 16820960

6

Cyproheptadine displays preclinical activity in myeloma and leukemia.

Mao X, Liang SB, Hurren R, Gronda M, Chow S, Xu GW, Wang X, Beheshti Zavareh R, Jamal N, Messner H, Hedley DW, Datti A, Wrana JL, Zhu Y, Shi CX, Lee K, Tiedemann R, Trudel S, Stewart AK, Schimmer AD. Mao X, et al. Among authors: hedley dw. Blood. 2008 Aug 1;112(3):760-9. doi: 10.1182/blood-2008-02-142687. Epub 2008 May 23. Blood. 2008. PMID: 18502826 Free article.

7

Relationships between the mitochondrial permeability transition and oxidative stress during ara-C toxicity.

Backway KL, McCulloch EA, Chow S, Hedley DW. Backway KL, et al. Among authors: hedley dw. Cancer Res. 1997 Jun 15;57(12):2446-51. Cancer Res. 1997. PMID: 9192824

8

Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells.

Ng SSW, Tsao MS, Chow S, Hedley DW. Ng SSW, et al. Among authors: hedley dw. Cancer Res. 2000 Oct 1;60(19):5451-5. Cancer Res. 2000. PMID: 11034087

9

BAD induces apoptosis in cells over-expressing Bcl-2 or Bcl-xL without loss of mitochondrial membrane potential.

Schimmer AD, Hedley DW, Pham NA, Chow S, Minden MD. Schimmer AD, et al. Among authors: hedley dw. Leuk Lymphoma. 2001 Jul;42(3):429-43. doi: 10.3109/10428190109064600. Leuk Lymphoma. 2001. PMID: 11699408

10

Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells.

Tong FK, Chow S, Hedley D. Tong FK, et al. Cytometry B Clin Cytom. 2006 May;70(3):107-14. doi: 10.1002/cyto.b.20092. Cytometry B Clin Cytom. 2006. PMID: 16498671 Free article. Clinical Trial.

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