Little S - Search Results

1

Evaluation of azasterols as anti-parasitics.

Gros L, Lorente SO, Jimenez CJ, Yardley V, Rattray L, Wharton H, Little S, Croft SL, Ruiz-Perez LM, Gonzalez-Pacanowska D, Gilbert IH. Gros L, et al. Among authors: little s. J Med Chem. 2006 Oct 5;49(20):6094-103. doi: 10.1021/jm060290f. J Med Chem. 2006. PMID: 17004723

2

Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents.

Coro J, Atherton R, Little S, Wharton H, Yardley V, Alvarez A Jr, Súarez M, Pérez R, Rodríguez H. Coro J, et al. Among authors: little s. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1312-5. doi: 10.1016/j.bmcl.2005.11.060. Epub 2005 Dec 15. Bioorg Med Chem Lett. 2006. PMID: 16343898

3

Synthesis and in vitro protozoocidal activity of diazabicyclic benzotropolone derivatives.

Khrizman A, Moulthrop JS, Little S, Wharton H, Yardley V, Moyna G. Khrizman A, et al. Among authors: little s. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4183-6. doi: 10.1016/j.bmcl.2007.05.044. Epub 2007 May 18. Bioorg Med Chem Lett. 2007. PMID: 17532634

4

Application of multicomponent reactions to antimalarial drug discovery. Part 3: discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro.

Musonda CC, Little S, Yardley V, Chibale K. Musonda CC, et al. Among authors: little s. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4733-6. doi: 10.1016/j.bmcl.2007.06.070. Epub 2007 Jun 27. Bioorg Med Chem Lett. 2007. PMID: 17644333

5

Synthesis of aminoquinoline-based aminoalcohols and oxazolidinones and their antiplasmodial activity.

Kobarfard F, Yardley V, Little S, Daryaee F, Chibale K. Kobarfard F, et al. Among authors: little s. Chem Biol Drug Des. 2012 Mar;79(3):326-31. doi: 10.1111/j.1747-0285.2011.01278.x. Epub 2012 Jan 11. Chem Biol Drug Des. 2012. PMID: 22129095

6

Synthesis and in vitro protozoocidal evaluation of novel diazabicyclic tropolone derivatives.

Khrizman A, Slack RD, Remsing RC, Little S, Yardley V, Moyna G. Khrizman A, et al. Among authors: little s. Arch Pharm (Weinheim). 2007 Nov;340(11):569-76. doi: 10.1002/ardp.200700143. Arch Pharm (Weinheim). 2007. PMID: 17924365

7

Synthesis and antiprotozoal evaluation of new N4-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones).

Coro J, Little S, Yardley V, Suárez M, Rodríguez H, Martín N, Perez-Pineiro R. Coro J, et al. Among authors: little s. Arch Pharm (Weinheim). 2008 Nov;341(11):708-13. doi: 10.1002/ardp.200800011. Arch Pharm (Weinheim). 2008. PMID: 18720341

8

Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates.

Ferreira CL, Ewart CB, Barta CA, Little S, Yardley V, Martins C, Polishchuk E, Smith PJ, Moss JR, Merkel M, Adam MJ, Orvig C. Ferreira CL, et al. Among authors: little s. Inorg Chem. 2006 Oct 2;45(20):8414-22. doi: 10.1021/ic061166p. Inorg Chem. 2006. PMID: 16999442

9

A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme.

Bauer H, Fritz-Wolf K, Winzer A, Kühner S, Little S, Yardley V, Vezin H, Palfey B, Schirmer RH, Davioud-Charvet E. Bauer H, et al. Among authors: little s. J Am Chem Soc. 2006 Aug 23;128(33):10784-94. doi: 10.1021/ja061155v. J Am Chem Soc. 2006. PMID: 16910673

10

2,4-diarylthiazole antiprion compounds as a novel structural class of antimalarial leads.

Thompson MJ, Louth JC, Little SM, Chen B, Coldham I. Thompson MJ, et al. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3644-7. doi: 10.1016/j.bmcl.2011.04.090. Epub 2011 Apr 28. Bioorg Med Chem Lett. 2011. PMID: 21570837

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