Cihlar T - Search Results

1

Mechanism of active renal tubular efflux of tenofovir.

Ray AS, Cihlar T, Robinson KL, Tong L, Vela JE, Fuller MD, Wieman LM, Eisenberg EJ, Rhodes GR. Ray AS, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2006 Oct;50(10):3297-304. doi: 10.1128/AAC.00251-06. Antimicrob Agents Chemother. 2006. PMID: 17005808 Free PMC article.

2

Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase.

Mendel DB, Cihlar T, Moon K, Chen MS. Mendel DB, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 1997 Mar;41(3):641-6. doi: 10.1128/AAC.41.3.641. Antimicrob Agents Chemother. 1997. PMID: 9056007 Free PMC article.

3

Expression of the catalytic subunit (UL54) and the accessory protein (UL44) of human cytomegalovirus DNA polymerase in a coupled in vitro transcription/translation system.

Cihlar T, Fuller MD, Cherrington JM. Cihlar T, et al. Protein Expr Purif. 1997 Nov;11(2):209-18. doi: 10.1006/prep.1997.0781. Protein Expr Purif. 1997. PMID: 9367818

4

Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.

Cihlar T, Fuller MD, Cherrington JM. Cihlar T, et al. J Virol. 1998 Jul;72(7):5927-36. doi: 10.1128/JVI.72.7.5927-5936.1998. J Virol. 1998. PMID: 9621055 Free PMC article.

5

Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity.

Miller MD, Lamy PD, Fuller MD, Mulato AS, Margot NA, Cihlar T, Cherrington JM. Miller MD, et al. Among authors: cihlar t. Mol Pharmacol. 1998 Aug;54(2):291-7. doi: 10.1124/mol.54.2.291. Mol Pharmacol. 1998. PMID: 9687570

6

A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.

Cihlar T, Fuller MD, Mulato AS, Cherrington JM. Cihlar T, et al. Virology. 1998 Sep 1;248(2):382-93. doi: 10.1006/viro.1998.9299. Virology. 1998. PMID: 9721246 Free article.

7

The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.

Cihlar T, Lin DC, Pritchard JB, Fuller MD, Mendel DB, Sweet DH. Cihlar T, et al. Mol Pharmacol. 1999 Sep;56(3):570-80. doi: 10.1124/mol.56.3.570. Mol Pharmacol. 1999. PMID: 10462545

8

Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.

Ho ES, Lin DC, Mendel DB, Cihlar T. Ho ES, et al. Among authors: cihlar t. J Am Soc Nephrol. 2000 Mar;11(3):383-393. doi: 10.1681/ASN.V113383. J Am Soc Nephrol. 2000. PMID: 10703662

9

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Mulato AS, Ho ES, Cihlar T. Mulato AS, et al. Among authors: cihlar t. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. J Pharmacol Exp Ther. 2000. PMID: 10991954

10

Expression and characterization of soluble human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein.

Wang ZM, Tong LL, Grant D, Cihlar T. Wang ZM, et al. Among authors: cihlar t. J Virol Methods. 2001 Oct;98(1):53-61. doi: 10.1016/s0166-0934(01)00355-x. J Virol Methods. 2001. PMID: 11543884

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