Lamb J - Search Results

1

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.

Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR. Hieronymus H, et al. Among authors: lamb j. Cancer Cell. 2006 Oct;10(4):321-30. doi: 10.1016/j.ccr.2006.09.005. Epub 2006 Sep 28. Cancer Cell. 2006. PMID: 17010675 Free article.

2

A method for high-throughput gene expression signature analysis.

Peck D, Crawford ED, Ross KN, Stegmaier K, Golub TR, Lamb J. Peck D, et al. Among authors: lamb j. Genome Biol. 2006;7(7):R61. doi: 10.1186/gb-2006-7-7-r61. Genome Biol. 2006. PMID: 16859521 Free PMC article.

3

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.

Wei G, Twomey D, Lamb J, Schlis K, Agarwal J, Stam RW, Opferman JT, Sallan SE, den Boer ML, Pieters R, Golub TR, Armstrong SA. Wei G, et al. Among authors: lamb j. Cancer Cell. 2006 Oct;10(4):331-42. doi: 10.1016/j.ccr.2006.09.006. Epub 2006 Sep 28. Cancer Cell. 2006. PMID: 17010674 Free article.

4

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR. Lamb J, et al. Science. 2006 Sep 29;313(5795):1929-35. doi: 10.1126/science.1132939. Science. 2006. PMID: 17008526

5

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer.

Lamb J, Ramaswamy S, Ford HL, Contreras B, Martinez RV, Kittrell FS, Zahnow CA, Patterson N, Golub TR, Ewen ME. Lamb J, et al. Cell. 2003 Aug 8;114(3):323-34. doi: 10.1016/s0092-8674(03)00570-1. Cell. 2003. PMID: 12914697 Free article.

6

The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.

Zimmer M, Lamb J, Ebert BL, Lynch M, Neil C, Schmidt E, Golub TR, Iliopoulos O. Zimmer M, et al. Among authors: lamb j. Cancer Res. 2010 Apr 15;70(8):3071-9. doi: 10.1158/0008-5472.CAN-09-2877. Epub 2010 Mar 30. Cancer Res. 2010. PMID: 20354189 Free PMC article.

7

MicroRNA expression profiles classify human cancers.

Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. Lu J, et al. Among authors: lamb j. Nature. 2005 Jun 9;435(7043):834-8. doi: 10.1038/nature03702. Nature. 2005. PMID: 15944708

8

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.

Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR. Subramanian A, et al. Among authors: lamb j. Cell. 2017 Nov 30;171(6):1437-1452.e17. doi: 10.1016/j.cell.2017.10.049. Cell. 2017. PMID: 29195078 Free PMC article.

9

Light-controlled modulation of gene expression by chemical optoepigenetic probes.

Reis SA, Ghosh B, Hendricks JA, Szantai-Kis DM, Törk L, Ross KN, Lamb J, Read-Button W, Zheng B, Wang H, Salthouse C, Haggarty SJ, Mazitschek R. Reis SA, et al. Among authors: lamb j. Nat Chem Biol. 2016 May;12(5):317-23. doi: 10.1038/nchembio.2042. Epub 2016 Mar 14. Nat Chem Biol. 2016. PMID: 26974814 Free PMC article.

10

Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing.

Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Zimmer M, et al. Among authors: lamb j. Mol Cell. 2008 Dec 26;32(6):838-48. doi: 10.1016/j.molcel.2008.12.004. Mol Cell. 2008. PMID: 19111663 Free PMC article.

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