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Synergistic effects of chemotherapeutic drugs in lymphoma cells are associated with down-regulation of inhibitor of apoptosis proteins (IAPs), prostate-apoptosis-response-gene 4 (Par-4), death-associated protein (Daxx) and with enforced caspase activation.
Chow KU, Nowak D, Boehrer S, Ruthardt M, Knau A, Hoelzer D, Mitrou PS, Weidmann E. Chow KU, et al. Among authors: weidmann e. Biochem Pharmacol. 2003 Sep 1;66(5):711-24. doi: 10.1016/s0006-2952(03)00410-6. Biochem Pharmacol. 2003. PMID: 12948851
Mitomycin C, 5-fluorouracil, leucovorin, and oxaliplatin as a salvage therapy for patients with cisplatin-resistant advanced gastric cancer: a phase I dose escalation trial.
Al-Batran SE, Kerber A, Atmaca A, Dechow C, Reitsamer E, Schmidt S, Kolassa Y, Neumann A, Weidmann E, Hartmann JT, Jäger E. Al-Batran SE, et al. Among authors: weidmann e. Onkologie. 2007 Feb;30(1-2):29-34. doi: 10.1159/000097768. Epub 2007 Jan 26. Onkologie. 2007. PMID: 17264523 Clinical Trial.
Induction of apoptosis by 2-chloro-2'deoxyadenosine (2-CdA) alone and in combination with other cytotoxic drugs: synergistic effects on normal and neoplastic lymphocytes by addition of doxorubicin and mitoxantrone.
Chow KU, Rummel MJ, Weidmann E, Ries J, Jantschke P, Boehrer S, Pourebrahim F, Napieralski S, Stein J, Martin H, Hoelzer D, Mitrou PS. Chow KU, et al. Among authors: weidmann e. Leuk Lymphoma. 2000 Feb;36(5-6):559-67. doi: 10.3109/10428190009148404. Leuk Lymphoma. 2000. PMID: 10784401
Induction of apoptosis by cladribine (2-CdA), gemcitabine and other chemotherapeutic drugs on CD34+/CD38+ and CD34+/CD38- hematopoietic progenitor cells: selective effects of doxorubicin and 2-CdA with protection of immature cells.
Chow KU, Boehrer S, Bojunga J, Stieler M, Rummel MJ, Fauth F, Schneider B, Martin H, Hoelzer D, Weidmann E, Mitrou PS. Chow KU, et al. Among authors: weidmann e. Leuk Lymphoma. 2002 Feb;43(2):377-84. doi: 10.1080/10428190290006198. Leuk Lymphoma. 2002. PMID: 11999573
129 results