Sun D - Search Results

1

Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.

Fang L, Battisti RF, Cheng H, Reigan P, Xin Y, Shen J, Ross D, Chan KK, Martin EW Jr, Wang PG, Sun D. Fang L, et al. Among authors: sun d. J Med Chem. 2006 Oct 19;49(21):6290-7. doi: 10.1021/jm060647f. J Med Chem. 2006. PMID: 17034135 Free PMC article.

2

Synthesis and enzyme-specific activation of carbohydrate-geldanamycin conjugates with potent anticancer activity.

Cheng H, Cao X, Xian M, Fang L, Cai TB, Ji JJ, Tunac JB, Sun D, Wang PG. Cheng H, et al. Among authors: sun d. J Med Chem. 2005 Jan 27;48(2):645-52. doi: 10.1021/jm049693a. J Med Chem. 2005. PMID: 15658879

3

Pharmacokinetics and clinical evaluation of 125I-radiolabeled humanized CC49 monoclonal antibody (HuCC49deltaC(H)2) in recurrent and metastatic colorectal cancer patients.

Xiao J, Horst S, Hinkle G, Cao X, Kocak E, Fang J, Young D, Khazaeli M, Agnese D, Sun D, Martin E Jr. Xiao J, et al. Among authors: sun d. Cancer Biother Radiopharm. 2005 Feb;20(1):16-26. doi: 10.1089/cbr.2005.20.16. Cancer Biother Radiopharm. 2005. PMID: 15778575 Clinical Trial.

4

Syntheses and biological activities of rebeccamycin analogues with uncommon sugars.

Zhang G, Shen J, Cheng H, Zhu L, Fang L, Luo S, Muller MT, Lee GE, Wei L, Du Y, Sun D, Wang PG. Zhang G, et al. Among authors: sun d. J Med Chem. 2005 Apr 7;48(7):2600-11. doi: 10.1021/jm0493764. J Med Chem. 2005. PMID: 15801850

5

Syntheses and biological activities of daunorubicin analogs with uncommon sugars.

Zhu L, Cao X, Chen W, Zhang G, Sun D, Wang PG. Zhu L, et al. Among authors: sun d. Bioorg Med Chem. 2005 Dec 1;13(23):6381-7. doi: 10.1016/j.bmc.2005.06.053. Epub 2005 Aug 1. Bioorg Med Chem. 2005. PMID: 16055335

6

Syntheses and biological activities of disaccharide daunorubicins.

Zhang G, Fang L, Zhu L, Aimiuwu JE, Shen J, Cheng H, Muller MT, Lee GE, Sun D, Wang PG. Zhang G, et al. Among authors: sun d. J Med Chem. 2005 Aug 11;48(16):5269-78. doi: 10.1021/jm050144u. J Med Chem. 2005. PMID: 16078845

7

Syntheses and biological activity of bisdaunorubicins.

Zhang G, Fang L, Zhu L, Sun D, Wang PG. Zhang G, et al. Among authors: sun d. Bioorg Med Chem. 2006 Jan 15;14(2):426-34. doi: 10.1016/j.bmc.2005.08.014. Epub 2005 Sep 22. Bioorg Med Chem. 2006. PMID: 16182536

8

Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance.

Fang L, Zhang G, Li C, Zheng X, Zhu L, Xiao JJ, Szakacs G, Nadas J, Chan KK, Wang PG, Sun D. Fang L, et al. Among authors: sun d. J Med Chem. 2006 Feb 9;49(3):932-41. doi: 10.1021/jm050800q. J Med Chem. 2006. PMID: 16451059

9

Syntheses and biological activities of 3'-azido disaccharide analogues of daunorubicin against drug-resistant leukemia.

Zhang G, Fang L, Zhu L, Zhong Y, Wang PG, Sun D. Zhang G, et al. Among authors: sun d. J Med Chem. 2006 Mar 9;49(5):1792-9. doi: 10.1021/jm050916m. J Med Chem. 2006. PMID: 16509594

10

Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D. Cao X, et al. Among authors: sun d. Pharm Res. 2006 Aug;23(8):1675-86. doi: 10.1007/s11095-006-9041-2. Pharm Res. 2006. PMID: 16841194 Review.

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