Wild C - Search Results

1

Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight.

Cushman M, Wang PL, Chang SH, Wild C, De Clercq E, Schols D, Goldman ME, Bowen JA. Cushman M, et al. Among authors: wild c. J Med Chem. 1991 Jan;34(1):329-37. doi: 10.1021/jm00105a052. J Med Chem. 1991. PMID: 1704065

2

Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer.

Kuang Y, Ye N, Kyani A, Ljungman M, Paulsen M, Chen H, Zhou M, Wild C, Chen H, Zhou J, Neamati N. Kuang Y, et al. Among authors: wild c. J Med Chem. 2022 Apr 28;65(8):6133-6156. doi: 10.1021/acs.jmedchem.1c02207. Epub 2022 Apr 19. J Med Chem. 2022. PMID: 35439009 Free PMC article.

3

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Ye N, Ester CD, Xiong A, White MA, Shen Q, Zhou J. Ding C, et al. Among authors: wild c. J Med Chem. 2013 Nov 14;56(21):8814-25. doi: 10.1021/jm401248x. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24128046 Free PMC article.

4

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).

Chen H, Yang Z, Ding C, Xiong A, Wild C, Wang L, Ye N, Cai G, Flores RM, Ding Y, Shen Q, Zhou J. Chen H, et al. Among authors: wild c. Eur J Med Chem. 2014 Jul 23;82:195-203. doi: 10.1016/j.ejmech.2014.05.049. Epub 2014 May 22. Eur J Med Chem. 2014. PMID: 24904966 Free PMC article.

5

Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT_2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties.

Wold EA, Garcia EJ, Wild CT, Miszkiel JM, Soto CA, Chen J, Pazdrak K, Fox RG, Anastasio NC, Cunningham KA, Zhou J. Wold EA, et al. Among authors: wild ct. J Med Chem. 2020 Jul 23;63(14):7529-7544. doi: 10.1021/acs.jmedchem.9b01953. Epub 2020 Jul 7. J Med Chem. 2020. PMID: 32567857 Free PMC article.

6

Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility.

Ding C, Zhang Y, Chen H, Yang Z, Wild C, Chu L, Liu H, Shen Q, Zhou J. Ding C, et al. Among authors: wild c. J Med Chem. 2013 Jun 27;56(12):5048-58. doi: 10.1021/jm400367n. Epub 2013 Jun 19. J Med Chem. 2013. PMID: 23746196 Free PMC article.

7

Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.

Ye N, Zhu Y, Chen H, Liu Z, Mei FC, Wild C, Chen H, Cheng X, Zhou J. Ye N, et al. Among authors: wild c. J Med Chem. 2015 Aug 13;58(15):6033-47. doi: 10.1021/acs.jmedchem.5b00635. Epub 2015 Jul 16. J Med Chem. 2015. PMID: 26151319 Free PMC article.

8

Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

Chen H, Wild C, Zhou X, Ye N, Cheng X, Zhou J. Chen H, et al. Among authors: wild c. J Med Chem. 2014 May 8;57(9):3651-65. doi: 10.1021/jm401425e. Epub 2013 Nov 27. J Med Chem. 2014. PMID: 24256330 Free PMC article. Review.

9

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT_2C Receptor.

Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J. Wild CT, et al. J Med Chem. 2019 Jan 10;62(1):288-305. doi: 10.1021/acs.jmedchem.8b00401. Epub 2018 Apr 13. J Med Chem. 2019. PMID: 29620897 Free PMC article.

10

A combined bioinformatics and chemoinformatics approach for developing asymmetric bivalent AMPA receptor positive allosteric modulators as neuroprotective agents.

Chen H, Wang CZ, Ding C, Wild C, Copits B, Swanson GT, Johnson KM, Zhou J. Chen H, et al. Among authors: wild c. ChemMedChem. 2013 Feb;8(2):226-30. doi: 10.1002/cmdc.201200554. Epub 2012 Dec 20. ChemMedChem. 2013. PMID: 23281122 Free PMC article.

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