Tharnish PM - Search Results

1

Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication.

Stuyver LJ, McBrayer TR, Tharnish PM, Clark J, Hollecker L, Lostia S, Nachman T, Grier J, Bennett MA, Xie MY, Schinazi RF, Morrey JD, Julander JL, Furman PA, Otto MJ. Stuyver LJ, et al. Among authors: tharnish pm. Antivir Chem Chemother. 2006;17(2):79-87. doi: 10.1177/095632020601700203. Antivir Chem Chemother. 2006. PMID: 17042329 Free article.

2

Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture.

Stuyver LJ, Whitaker T, McBrayer TR, Hernandez-Santiago BI, Lostia S, Tharnish PM, Ramesh M, Chu CK, Jordan R, Shi J, Rachakonda S, Watanabe KA, Otto MJ, Schinazi RF. Stuyver LJ, et al. Among authors: tharnish pm. Antimicrob Agents Chemother. 2003 Jan;47(1):244-54. doi: 10.1128/AAC.47.1.244-254.2003. Antimicrob Agents Chemother. 2003. PMID: 12499198 Free PMC article.

3

N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.

Shi J, Mathew JS, Tharnish PM, Rachakonda S, Pai SB, Adams M, Grier JP, Gallagher K, Zhang H, Wu JT, Shi G, Geleziunas R, Erickson-Viitanen S, Stuyver L, Otto MJ, Watanabe KA, Schinazi RF. Shi J, et al. Among authors: tharnish pm. Antivir Chem Chemother. 2003 Mar;14(2):81-90. doi: 10.1177/095632020301400203. Antivir Chem Chemother. 2003. PMID: 12856919 Free article.

4

Dynamics of subgenomic hepatitis C virus replicon RNA levels in Huh-7 cells after exposure to nucleoside antimetabolites.

Stuyver LJ, McBrayer TR, Tharnish PM, Hassan AE, Chu CK, Pankiewicz KW, Watanabe KA, Schinazi RF, Otto MJ. Stuyver LJ, et al. Among authors: tharnish pm. J Virol. 2003 Oct;77(19):10689-94. doi: 10.1128/jvi.77.19.10689-10694.2003. J Virol. 2003. PMID: 12970456 Free PMC article.

5

Inhibition of the subgenomic hepatitis C virus replicon in huh-7 cells by 2'-deoxy-2'-fluorocytidine.

Stuyver LJ, McBrayer TR, Whitaker T, Tharnish PM, Ramesh M, Lostia S, Cartee L, Shi J, Hobbs A, Schinazi RF, Watanabe KA, Otto MJ. Stuyver LJ, et al. Among authors: tharnish pm. Antimicrob Agents Chemother. 2004 Feb;48(2):651-4. doi: 10.1128/AAC.48.2.651-654.2004. Antimicrob Agents Chemother. 2004. PMID: 14742230 Free PMC article.

6

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.

Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Sidwell RW, Stuyver LJ, Otto MJ, Schinazi RF, Watanabe KA. Wang P, et al. Among authors: tharnish pm. J Med Chem. 2004 Nov 18;47(24):6100-3. doi: 10.1021/jm0401210. J Med Chem. 2004. PMID: 15537363

7

Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Tharnish PM, McBrayer TR, Stuyver LJ, Otto MJ, Chu CK, Schinazi RF, Watanabe KA. Shi J, et al. Among authors: tharnish pm. Bioorg Med Chem. 2005 Mar 1;13(5):1641-52. doi: 10.1016/j.bmc.2004.12.011. Bioorg Med Chem. 2005. PMID: 15698782

8

Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.

Clark JL, Hollecker L, Mason JC, Stuyver LJ, Tharnish PM, Lostia S, McBrayer TR, Schinazi RF, Watanabe KA, Otto MJ, Furman PA, Stec WJ, Patterson SE, Pankiewicz KW. Clark JL, et al. Among authors: tharnish pm. J Med Chem. 2005 Aug 25;48(17):5504-8. doi: 10.1021/jm0502788. J Med Chem. 2005. PMID: 16107149

9

Synthesis and structure-activity relationships of novel anti-hepatitis C agents: N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one derivatives.

Wang P, Du J, Rachakonda S, Chun BK, Tharnish PM, Stuyver LJ, Otto MJ, Schinazi RF, Watanabe KA. Wang P, et al. Among authors: tharnish pm. J Med Chem. 2005 Oct 6;48(20):6454-60. doi: 10.1021/jm058223t. J Med Chem. 2005. PMID: 16190771

10

Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Hassan AE, Tharnish PM, McBrayer TR, Lostia S, Stuyver LJ, Watanabe KA, Chu CK, Schinazi RF, Otto MJ. Shi J, et al. Among authors: tharnish pm. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):875-9. doi: 10.1081/ncn-200059224. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248053

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