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Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Carmo H, Brulport M, Hermes M, Oesch F, Silva R, Ferreira LM, Branco PS, Boer Dd, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG. Carmo H, et al. Among authors: hengstler jg. Pharmacogenet Genomics. 2006 Nov;16(11):789-99. doi: 10.1097/01.fpc.0000230419.05221.fc. Pharmacogenet Genomics. 2006. PMID: 17047487
CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).
Carmo H, Brulport M, Hermes M, Oesch F, de Boer D, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG. Carmo H, et al. Among authors: hengstler jg. Toxicology. 2007 Jan 18;229(3):236-44. doi: 10.1016/j.tox.2006.10.024. Epub 2006 Dec 5. Toxicology. 2007. PMID: 17156908
Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.
Carmo H, Hengstler JG, de Boer D, Ringel M, Carvalho F, Fernandes E, Remião F, dos Reys LA, Oesch F, de Lourdes Bastos M. Carmo H, et al. Among authors: hengstler jg. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):198-205. doi: 10.1007/s00210-003-0850-0. Epub 2003 Dec 16. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14676987
Metabolic detoxification: implications for thresholds.
Oesch F, Herrero ME, Hengstler JG, Lohmann M, Arand M. Oesch F, et al. Among authors: hengstler jg. Toxicol Pathol. 2000 May-Jun;28(3):382-7. doi: 10.1177/019262330002800305. Toxicol Pathol. 2000. PMID: 10862554 Review.
562 results