Ghosal A - Search Results

1

Identification of unstable metabolites of Lonafarnib using liquid chromatography-quadrupole time-of-flight mass spectrometry, stable isotope incorporation and ion source temperature alteration.

Tong W, Chowdhury SK, Su AD, Feng W, Ghosal A, Alton KB. Tong W, et al. Among authors: ghosal a. J Mass Spectrom. 2006 Nov;41(11):1430-41. doi: 10.1002/jms.1114. J Mass Spectrom. 2006. PMID: 17051523

2

Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar).

Ghosal A, Chowdhury SK, Tong W, Hapangama N, Yuan Y, Su AD, Zbaida S. Ghosal A, et al. Drug Metab Dispos. 2006 Apr;34(4):628-35. doi: 10.1124/dmd.105.007906. Epub 2006 Jan 27. Drug Metab Dispos. 2006. PMID: 16443667

3

A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) for extraction of drug metabolites in liquid chromatography/mass spectrometry data from biological matrices.

Zhu P, Ding W, Tong W, Ghosal A, Alton K, Chowdhury S. Zhu P, et al. Among authors: ghosal a. Rapid Commun Mass Spectrom. 2009 Jun;23(11):1563-72. doi: 10.1002/rcm.4041. Rapid Commun Mass Spectrom. 2009. PMID: 19408276

4

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 351125, a CCR5 antagonist.

Ghosal A, Chowdhury SK, Gupta S, Yuan Y, Iannucci R, Zhang H, Zbaida S, Patrick JE, Alton KB. Ghosal A, et al. Xenobiotica. 2005 May;35(5):405-17. doi: 10.1080/00498250500136569. Xenobiotica. 2005. PMID: 16012074

5

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S. Ghosal A, et al. Drug Metab Dispos. 2004 Feb;32(2):267-71. doi: 10.1124/dmd.32.2.267. Drug Metab Dispos. 2004. PMID: 14744950

6

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S. Ghosal A, et al. Drug Metab Dispos. 2004 Mar;32(3):314-20. doi: 10.1124/dmd.32.3.314. Drug Metab Dispos. 2004. PMID: 14977865

7

Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist.

Ghosal A, Ramanathan R, Yuan Y, Hapangama N, Chowdhury SK, Kishnani NS, Alton KB. Ghosal A, et al. Drug Metab Dispos. 2007 Dec;35(12):2186-95. doi: 10.1124/dmd.107.017517. Epub 2007 Sep 7. Drug Metab Dispos. 2007. PMID: 17827338

8

Metabolism of loratadine and further characterization of its in vitro metabolites.

Ghosal A, Gupta S, Ramanathan R, Yuan Y, Lu X, Su AD, Alvarez N, Zbaida S, Chowdhury SK, Alton KB. Ghosal A, et al. Drug Metab Lett. 2009 Aug;3(3):162-70. doi: 10.2174/187231209789352067. Epub 2009 Aug 1. Drug Metab Lett. 2009. PMID: 19702548

9

Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.

Ghosal A, Lu X, Penner N, Gao L, Ramanathan R, Chowdhury SK, Kishnani NS, Alton KB. Ghosal A, et al. Drug Metab Dispos. 2011 Jan;39(1):30-8. doi: 10.1124/dmd.110.035493. Epub 2010 Oct 6. Drug Metab Dispos. 2011. PMID: 20926621

10

Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.

Ghosal A, Yuan Y, Tong W, Su AD, Gu C, Chowdhury SK, Kishnani NS, Alton KB. Ghosal A, et al. Drug Metab Dispos. 2011 Mar;39(3):510-21. doi: 10.1124/dmd.110.036996. Epub 2010 Dec 1. Drug Metab Dispos. 2011. PMID: 21123164

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