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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
Weydt P, Pineda VV, Torrence AE, Libby RT, Satterfield TF, Lazarowski ER, Gilbert ML, Morton GJ, Bammler TK, Strand AD, Cui L, Beyer RP, Easley CN, Smith AC, Krainc D, Luquet S, Sweet IR, Schwartz MW, La Spada AR. Weydt P, et al. Cell Metab. 2006 Nov;4(5):349-62. doi: 10.1016/j.cmet.2006.10.004. Epub 2006 Oct 19. Cell Metab. 2006. PMID: 17055784 Free article.
Targeting toxic proteins for turnover.
La Spada AR, Weydt P. La Spada AR, et al. Among authors: weydt p. Nat Med. 2005 Oct;11(10):1052-3. doi: 10.1038/nm1005-1052. Nat Med. 2005. PMID: 16211038 No abstract available.
Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington's disease.
Jesse S, Bayer H, Alupei MC, Zügel M, Mulaw M, Tuorto F, Malmsheimer S, Singh K, Steinacker J, Schumann U, Ludolph AC, Scharffetter-Kochanek K, Witting A, Weydt P, Iben S. Jesse S, et al. Among authors: weydt p. Sci Rep. 2017 Aug 17;7(1):8513. doi: 10.1038/s41598-017-09148-7. Sci Rep. 2017. PMID: 28819135 Free PMC article.
Thermoregulatory disorders in Huntington disease.
Weydt P, Dupuis L, Petersen Å. Weydt P, et al. Handb Clin Neurol. 2018;157:761-775. doi: 10.1016/B978-0-444-64074-1.00047-1. Handb Clin Neurol. 2018. PMID: 30459039 Review.
129 results