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Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis.
Mortensen JH, Godskesen LE, Jensen MD, Van Haaften WT, Klinge LG, Olinga P, Dijkstra G, Kjeldsen J, Karsdal MA, Bay-Jensen AC, Krag A. Mortensen JH, et al. Among authors: klinge lg. J Crohns Colitis. 2015 Oct;9(10):863-72. doi: 10.1093/ecco-jcc/jjv123. Epub 2015 Jul 17. J Crohns Colitis. 2015. PMID: 26188349 Clinical Trial.
Ulcerative colitis, Crohn's disease, and irritable bowel syndrome have different profiles of extracellular matrix turnover, which also reflects disease activity in Crohn's disease.
Mortensen JH, Manon-Jensen T, Jensen MD, Hägglund P, Klinge LG, Kjeldsen J, Krag A, Karsdal MA, Bay-Jensen AC. Mortensen JH, et al. Among authors: klinge lg. PLoS One. 2017 Oct 13;12(10):e0185855. doi: 10.1371/journal.pone.0185855. eCollection 2017. PLoS One. 2017. PMID: 29028807 Free PMC article.