Drusano GL - Search Results

1

Pharmacokinetic considerations and efficacy of levofloxacin in an inhalational anthrax (postexposure) rhesus monkey model.

Kao LM, Bush K, Barnewall R, Estep J, Thalacker FW, Olson PH, Drusano GL, Minton N, Chien S, Hemeryck A, Kelley MF. Kao LM, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 2006 Nov;50(11):3535-42. doi: 10.1128/AAC.00090-06. Antimicrob Agents Chemother. 2006. PMID: 17065619 Free PMC article.

2

Levofloxacin population pharmacokinetics and creation of a demographic model for prediction of individual drug clearance in patients with serious community-acquired infection.

Preston SL, Drusano GL, Berman AL, Fowler CL, Chow AT, Dornseif B, Reichl V, Natarajan J, Wong FA, Corrado M. Preston SL, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 1998 May;42(5):1098-104. doi: 10.1128/AAC.42.5.1098. Antimicrob Agents Chemother. 1998. PMID: 9593134 Free PMC article.

3

Pharmacokinetic studies of fluconazole in rabbits characterizing doses which achieve peak levels in serum and area under the concentration-time curve values which mimic those of high-dose fluconazole in humans.

Louie A, Liu QF, Drusano GL, Liu W, Mayers M, Anaissie E, Miller MH. Louie A, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 1998 Jun;42(6):1512-4. doi: 10.1128/AAC.42.6.1512. Antimicrob Agents Chemother. 1998. PMID: 9624506 Free PMC article.

4

A population pharmacokinetic analysis of the penetration of the prostate by levofloxacin.

Drusano GL, Preston SL, Van Guilder M, North D, Gombert M, Oefelein M, Boccumini L, Weisinger B, Corrado M, Kahn J. Drusano GL, et al. Antimicrob Agents Chemother. 2000 Aug;44(8):2046-51. doi: 10.1128/AAC.44.8.2046-2051.2000. Antimicrob Agents Chemother. 2000. PMID: 10898674 Free PMC article. Clinical Trial.

5

Use of preclinical data for selection of a phase II/III dose for evernimicin and identification of a preclinical MIC breakpoint.

Drusano GL, Preston SL, Hardalo C, Hare R, Banfield C, Andes D, Vesga O, Craig WA. Drusano GL, et al. Antimicrob Agents Chemother. 2001 Jan;45(1):13-22. doi: 10.1128/AAC.45.1.13-22.2001. Antimicrob Agents Chemother. 2001. PMID: 11120938 Free PMC article.

6

Pharmacodynamics of daptomycin in a murine thigh model of Staphylococcus aureus infection.

Louie A, Kaw P, Liu W, Jumbe N, Miller MH, Drusano GL. Louie A, et al. Among authors: drusano gl. Antimicrob Agents Chemother. 2001 Mar;45(3):845-51. doi: 10.1128/AAC.45.3.845-851.2001. Antimicrob Agents Chemother. 2001. PMID: 11181370 Free PMC article.

7

Pharmacodynamic evaluation of RWJ-270201, a novel neuraminidase inhibitor, in a lethal murine model of influenza predicts efficacy for once-daily dosing.

Drusano GL, Preston SL, Smee D, Bush K, Bailey K, Sidwell RW. Drusano GL, et al. Antimicrob Agents Chemother. 2001 Jul;45(7):2115-8. doi: 10.1128/AAC.45.7.2115-2118.2001. Antimicrob Agents Chemother. 2001. PMID: 11408232 Free PMC article.

8

Pharmacodynamics of abacavir in an in vitro hollow-fiber model system.

Drusano GL, Bilello PA, Symonds WT, Stein DS, McDowell J, Bye A, Bilello JA. Drusano GL, et al. Antimicrob Agents Chemother. 2002 Feb;46(2):464-70. doi: 10.1128/AAC.46.2.464-470.2002. Antimicrob Agents Chemother. 2002. PMID: 11796359 Free PMC article.

9

Levofloxacin penetration into epithelial lining fluid as determined by population pharmacokinetic modeling and monte carlo simulation.

Drusano GL, Preston SL, Gotfried MH, Danziger LH, Rodvold KA. Drusano GL, et al. Antimicrob Agents Chemother. 2002 Feb;46(2):586-9. doi: 10.1128/AAC.46.2.586-589.2002. Antimicrob Agents Chemother. 2002. PMID: 11796385 Free PMC article. Clinical Trial.

10

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy.

Jumbe N, Louie A, Leary R, Liu W, Deziel MR, Tam VH, Bachhawat R, Freeman C, Kahn JB, Bush K, Dudley MN, Miller MH, Drusano GL. Jumbe N, et al. Among authors: drusano gl. J Clin Invest. 2003 Jul;112(2):275-85. doi: 10.1172/JCI16814. J Clin Invest. 2003. PMID: 12865415 Free PMC article.

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