Marr E - Search Results

1

Expression, purification, crystallization and structure of human adipocyte lipid-binding protein (aP2).

Marr E, Tardie M, Carty M, Brown Phillips T, Wang IK, Soeller W, Qiu X, Karam G. Marr E, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt 11):1058-60. doi: 10.1107/S1744309106038656. Epub 2006 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17077479 Free PMC article.

2

A systematic study of 50S ribosomal subunit purification enabling robust crystallization.

McLellan TJ, Marr ES, Wondrack LM, Subashi TA, Aeed PA, Han S, Xu Z, Wang IK, Maguire BA. McLellan TJ, et al. Acta Crystallogr D Biol Crystallogr. 2009 Dec;65(Pt 12):1270-82. doi: 10.1107/S0907444909039043. Epub 2009 Nov 17. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19966413

3

Purification of the large ribosomal subunit via its association with the small subunit.

Simons SP, McLellan TJ, Aeed PA, Zaniewski RP, Desbonnet CR, Wondrack LM, Marr ES, Subashi TA, Dougherty TJ, Xu Z, Wang IK, LeMotte PK, Maguire BA. Simons SP, et al. Anal Biochem. 2009 Dec 1;395(1):77-85. doi: 10.1016/j.ab.2009.07.042. Epub 2009 Jul 30. Anal Biochem. 2009. PMID: 19646947

4

Crystal structures of interleukin 17A and its complex with IL-17 receptor A.

Liu S, Song X, Chrunyk BA, Shanker S, Hoth LR, Marr ES, Griffor MC. Liu S, et al. Nat Commun. 2013;4:1888. doi: 10.1038/ncomms2880. Nat Commun. 2013. PMID: 23695682 Free article.

5

Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa.

Han S, Zaniewski RP, Marr ES, Lacey BM, Tomaras AP, Evdokimov A, Miller JR, Shanmugasundaram V. Han S, et al. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22002-7. doi: 10.1073/pnas.1013092107. Epub 2010 Dec 6. Proc Natl Acad Sci U S A. 2010. PMID: 21135211 Free PMC article.

6

Structure-guided inhibitor design for human acetyl-coenzyme A carboxylase by interspecies active site conversion.

Rajamohan F, Marr E, Reyes AR, Landro JA, Anderson MD, Corbett JW, Dirico KJ, Harwood JH, Tu M, Vajdos FF. Rajamohan F, et al. Among authors: marr e. J Biol Chem. 2011 Dec 2;286(48):41510-41519. doi: 10.1074/jbc.M111.275396. Epub 2011 Sep 27. J Biol Chem. 2011. PMID: 21953464 Free PMC article.

7

Synthesis and structure based optimization of novel Akt inhibitors.

Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Lippa B, et al. Among authors: marr es. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. doi: 10.1016/j.bmcl.2008.04.034. Epub 2008 Apr 15. Bioorg Med Chem Lett. 2008. PMID: 18456494

8

Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

McClure KF, Abramov YA, Laird ER, Barberia JT, Cai W, Carty TJ, Cortina SR, Danley DE, Dipesa AJ, Donahue KM, Dombroski MA, Elliott NC, Gabel CA, Han S, Hynes TR, Lemotte PK, Mansour MN, Marr ES, Letavic MA, Pandit J, Ripin DB, Sweeney FJ, Tan D, Tao Y. McClure KF, et al. Among authors: marr es. J Med Chem. 2005 Sep 8;48(18):5728-37. doi: 10.1021/jm050346q. J Med Chem. 2005. PMID: 16134941

9

Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.

Chappie TA, Humphrey JM, Allen MP, Estep KG, Fox CB, Lebel LA, Liras S, Marr ES, Menniti FS, Pandit J, Schmidt CJ, Tu M, Williams RD, Yang FV. Chappie TA, et al. J Med Chem. 2007 Jan 25;50(2):182-5. doi: 10.1021/jm060653b. J Med Chem. 2007. PMID: 17228859

10

Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia.

Verhoest PR, Chapin DS, Corman M, Fonseca K, Harms JF, Hou X, Marr ES, Menniti FS, Nelson F, O'Connor R, Pandit J, Proulx-Lafrance C, Schmidt AW, Schmidt CJ, Suiciak JA, Liras S. Verhoest PR, et al. J Med Chem. 2009 Aug 27;52(16):5188-96. doi: 10.1021/jm900521k. J Med Chem. 2009. PMID: 19630403

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