Hammer RE - Search Results

1

Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice.

Lagace TA, Curtis DE, Garuti R, McNutt MC, Park SW, Prather HB, Anderson NN, Ho YK, Hammer RE, Horton JD. Lagace TA, et al. Among authors: hammer re. J Clin Invest. 2006 Nov;116(11):2995-3005. doi: 10.1172/JCI29383. J Clin Invest. 2006. PMID: 17080197 Free PMC article.

2

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.

Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G. Engelking LJ, et al. Among authors: hammer re. J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978. J Clin Invest. 2004. PMID: 15085196 Free PMC article.

3

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.

Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD. Rashid S, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. doi: 10.1073/pnas.0501652102. Epub 2005 Apr 1. Proc Natl Acad Sci U S A. 2005. PMID: 15805190 Free PMC article.

4

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS. Engelking LJ, et al. Among authors: hammer re. J Clin Invest. 2005 Sep;115(9):2489-98. doi: 10.1172/JCI25614. Epub 2005 Aug 11. J Clin Invest. 2005. PMID: 16100574 Free PMC article.

5

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL. Shimano H, et al. Among authors: hammer re. J Clin Invest. 1997 Mar 1;99(5):846-54. doi: 10.1172/JCI119248. J Clin Invest. 1997. PMID: 9062341 Free PMC article.

6

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, Horton JD. Shimano H, et al. Among authors: hammer re. J Clin Invest. 1997 Oct 15;100(8):2115-24. doi: 10.1172/JCI119746. J Clin Invest. 1997. PMID: 9329978 Free PMC article.

7

Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol.

Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, Cohen JC, Hobbs HH. Yu L, et al. Among authors: hammer re. J Clin Invest. 2002 Sep;110(5):671-80. doi: 10.1172/JCI16001. J Clin Invest. 2002. PMID: 12208868 Free PMC article.

8

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice.

Moon YA, Hammer RE, Horton JD. Moon YA, et al. Among authors: hammer re. J Lipid Res. 2009 Mar;50(3):412-423. doi: 10.1194/jlr.M800383-JLR200. Epub 2008 Oct 6. J Lipid Res. 2009. PMID: 18838740 Free PMC article.

9

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Rong S, et al. Among authors: hammer re. Elife. 2017 Feb 28;6:e25015. doi: 10.7554/eLife.25015. Elife. 2017. PMID: 28244871 Free PMC article.

10

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL. Shimano H, et al. Among authors: hammer re. J Clin Invest. 1996 Oct 1;98(7):1575-84. doi: 10.1172/JCI118951. J Clin Invest. 1996. PMID: 8833906 Free PMC article.

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