Phadke A - Search Results

1

Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block single-stranded viral RNA synthesis catalyzed by HCV replication complexes in vitro.

Yang W, Sun Y, Phadke A, Deshpande M, Huang M. Yang W, et al. Among authors: phadke a. Antimicrob Agents Chemother. 2007 Jan;51(1):338-42. doi: 10.1128/AAC.00498-06. Epub 2006 Nov 6. Antimicrob Agents Chemother. 2007. PMID: 17088480 Free PMC article.

2

Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in silico screening of the NS5B RdRp.

Louise-May S, Yang W, Nie X, Liu D, Deshpande MS, Phadke AS, Huang M, Agarwal A. Louise-May S, et al. Among authors: phadke as. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3905-9. doi: 10.1016/j.bmcl.2007.04.103. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17512198

3

Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity.

Gadhachanda VR, Eastman KJ, Wang Q, Phadke AS, Patel D, Yang W, Marlor CW, Deshpande M, Huang M, Wiles JA. Gadhachanda VR, et al. Among authors: phadke as. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3463-3471. doi: 10.1016/j.bmcl.2018.09.023. Epub 2018 Sep 18. Bioorg Med Chem Lett. 2018. PMID: 30290989

4

Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors.

Yang W, Zhao Y, Fabrycki J, Hou X, Nie X, Sanchez A, Phadke A, Deshpande M, Agarwal A, Huang M. Yang W, et al. Among authors: phadke a. Antimicrob Agents Chemother. 2008 Jun;52(6):2043-52. doi: 10.1128/AAC.01548-07. Epub 2008 Apr 14. Antimicrob Agents Chemother. 2008. PMID: 18411324 Free PMC article.

5

A highly sensitive and reproducible HCV RNA hybridization method valuable for antiviral drug discovery.

Zhao Y, Sanchez A, Nie X, Liu D, Hou X, Fabrycki J, Phadke A, Deshpande M, Huang M, Yang W. Zhao Y, et al. Among authors: phadke a. J Virol Methods. 2008 Jul;151(1):154-7. doi: 10.1016/j.jviromet.2008.03.027. Epub 2008 May 8. J Virol Methods. 2008. PMID: 18466983

6

ACH-806, an NS4A antagonist, inhibits hepatitis C virus replication by altering the composition of viral replication complexes.

Yang W, Sun Y, Hou X, Zhao Y, Fabrycki J, Chen D, Wang X, Agarwal A, Phadke A, Deshpande M, Huang M. Yang W, et al. Among authors: phadke a. Antimicrob Agents Chemother. 2013 Jul;57(7):3168-77. doi: 10.1128/AAC.02630-12. Epub 2013 Apr 29. Antimicrob Agents Chemother. 2013. PMID: 23629709 Free PMC article.

7

Small molecule inhibitors of E. coli primase, a novel bacterial target.

Agarwal A, Louise-May S, Thanassi JA, Podos SD, Cheng J, Thoma C, Liu C, Wiles JA, Nelson DM, Phadke AS, Bradbury BJ, Deshpande MS, Pucci MJ. Agarwal A, et al. Among authors: phadke as. Bioorg Med Chem Lett. 2007 May 15;17(10):2807-10. doi: 10.1016/j.bmcl.2007.02.056. Epub 2007 Feb 25. Bioorg Med Chem Lett. 2007. PMID: 17350255

8

Selenophene-containing inhibitors of type IIA bacterial topoisomerases.

Wiles JA, Phadke AS, Bradbury BJ, Pucci MJ, Thanassi JA, Deshpande M. Wiles JA, et al. Among authors: phadke as. J Med Chem. 2011 May 12;54(9):3418-25. doi: 10.1021/jm2002124. Epub 2011 Apr 13. J Med Chem. 2011. PMID: 21443219

9

Synthesis of well-defined tower-shaped 1,3,5-trisubstituted adamantanes incorporating a macrocyclic trilactam ring system.

Li Q, Jin C, Petukhov PA, Rukavishnikov AV, Zaikova TO, Phadke A, LaMunyon DH, Lee MD, Keana JF. Li Q, et al. Among authors: phadke a. J Org Chem. 2004 Feb 20;69(4):1010-9. doi: 10.1021/jo035640+. J Org Chem. 2004. PMID: 14961648

10

Feasibility and Acceptability of Universal Adult Screening for Chronic Hepatitis B in Primary Care Clinics.

Chu RV, Sarnala S, Doan TV, Jamal A, Phadke A, So S, So R, Pham H, Chaudhary J, Huang R, Kim G, Palaniappan L, Kim K, Srinivasan M. Chu RV, et al. Among authors: phadke a. AJPM Focus. 2024 May 17;3(6):100240. doi: 10.1016/j.focus.2024.100240. eCollection 2024 Dec. AJPM Focus. 2024. PMID: 39582739 Free PMC article.

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