Yang W - Search Results

1

Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block single-stranded viral RNA synthesis catalyzed by HCV replication complexes in vitro.

Yang W, Sun Y, Phadke A, Deshpande M, Huang M. Yang W, et al. Antimicrob Agents Chemother. 2007 Jan;51(1):338-42. doi: 10.1128/AAC.00498-06. Epub 2006 Nov 6. Antimicrob Agents Chemother. 2007. PMID: 17088480 Free PMC article.

2

Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in silico screening of the NS5B RdRp.

Louise-May S, Yang W, Nie X, Liu D, Deshpande MS, Phadke AS, Huang M, Agarwal A. Louise-May S, et al. Among authors: yang w. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3905-9. doi: 10.1016/j.bmcl.2007.04.103. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17512198

3

Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors.

Yang W, Zhao Y, Fabrycki J, Hou X, Nie X, Sanchez A, Phadke A, Deshpande M, Agarwal A, Huang M. Yang W, et al. Antimicrob Agents Chemother. 2008 Jun;52(6):2043-52. doi: 10.1128/AAC.01548-07. Epub 2008 Apr 14. Antimicrob Agents Chemother. 2008. PMID: 18411324 Free PMC article.

4

A highly sensitive and reproducible HCV RNA hybridization method valuable for antiviral drug discovery.

Zhao Y, Sanchez A, Nie X, Liu D, Hou X, Fabrycki J, Phadke A, Deshpande M, Huang M, Yang W. Zhao Y, et al. Among authors: yang w. J Virol Methods. 2008 Jul;151(1):154-7. doi: 10.1016/j.jviromet.2008.03.027. Epub 2008 May 8. J Virol Methods. 2008. PMID: 18466983

5

Studying HCV RNA synthesis in vitro with replication complexes.

Yang W, Huang M. Yang W, et al. Methods Mol Biol. 2009;510:177-84. doi: 10.1007/978-1-59745-394-3_13. Methods Mol Biol. 2009. PMID: 19009261

6

ACH-806, an NS4A antagonist, inhibits hepatitis C virus replication by altering the composition of viral replication complexes.

Yang W, Sun Y, Hou X, Zhao Y, Fabrycki J, Chen D, Wang X, Agarwal A, Phadke A, Deshpande M, Huang M. Yang W, et al. Antimicrob Agents Chemother. 2013 Jul;57(7):3168-77. doi: 10.1128/AAC.02630-12. Epub 2013 Apr 29. Antimicrob Agents Chemother. 2013. PMID: 23629709 Free PMC article.

7

Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity.

Gadhachanda VR, Eastman KJ, Wang Q, Phadke AS, Patel D, Yang W, Marlor CW, Deshpande M, Huang M, Wiles JA. Gadhachanda VR, et al. Among authors: yang w. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3463-3471. doi: 10.1016/j.bmcl.2018.09.023. Epub 2018 Sep 18. Bioorg Med Chem Lett. 2018. PMID: 30290989

8

Internal cleavages of hepatitis C virus NS3 induced by P1 mutations at the NS3/4A cleavage site.

Hou X, Yang W, Zhao Y, Agarwal A, Huang M. Hou X, et al. Among authors: yang w. Virology. 2009 Jan 20;383(2):271-8. doi: 10.1016/j.virol.2008.10.037. Epub 2008 Nov 25. Virology. 2009. PMID: 19036397 Free article.

9

Increased ratio of red cell distribution width to lymphocyte percentage as a new preoperative marker for unfavorable survival outcomes in upper tract urothelial carcinoma.

Hsieh YC, Cheng TH, Wang CA, Hu CY, Yang WH, Ou CH, Jan HC. Hsieh YC, et al. Among authors: yang wh. Biomed Rep. 2024 Dec 10;22(2):32. doi: 10.3892/br.2024.1910. eCollection 2025 Feb. Biomed Rep. 2024. PMID: 39720293 Free PMC article.

10

Clinical and genetic characterization of patients with late onset Wilson's disease.

Yang W, Yang Y, Wang H, Wang J, Zhang S. Yang W, et al. NPJ Genom Med. 2024 Dec 24;9(1):71. doi: 10.1038/s41525-024-00459-z. NPJ Genom Med. 2024. PMID: 39719440 Free article.

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