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Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance.
Lelliott CJ, Medina-Gomez G, Petrovic N, Kis A, Feldmann HM, Bjursell M, Parker N, Curtis K, Campbell M, Hu P, Zhang D, Litwin SE, Zaha VG, Fountain KT, Boudina S, Jimenez-Linan M, Blount M, Lopez M, Meirhaeghe A, Bohlooly-Y M, Storlien L, Strömstedt M, Snaith M, Oresic M, Abel ED, Cannon B, Vidal-Puig A. Lelliott CJ, et al. PLoS Biol. 2006 Nov;4(11):e369. doi: 10.1371/journal.pbio.0040369. PLoS Biol. 2006. PMID: 17090215 Free PMC article.
Digenic inheritance of severe insulin resistance in a human pedigree.
Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O'Rahilly S, Chatterjee VK, Schafer AJ. Savage DB, et al. Nat Genet. 2002 Aug;31(4):379-84. doi: 10.1038/ng926. Epub 2002 Jul 15. Nat Genet. 2002. PMID: 12118251
Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.
Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ. Meirhaeghe A, et al. Biochem J. 2003 Jul 1;373(Pt 1):155-65. doi: 10.1042/BJ20030200. Biochem J. 2003. PMID: 12678921 Free PMC article.
Nuclear receptor corepressor RIP140 regulates fat accumulation.
Leonardsson G, Steel JH, Christian M, Pocock V, Milligan S, Bell J, So PW, Medina-Gomez G, Vidal-Puig A, White R, Parker MG. Leonardsson G, et al. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8437-42. doi: 10.1073/pnas.0401013101. Epub 2004 May 20. Proc Natl Acad Sci U S A. 2004. PMID: 15155905 Free PMC article.
353 results