Beissert T - Search Results

1

BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility.

Zheng X, Güller S, Beissert T, Puccetti E, Ruthardt M. Zheng X, et al. Among authors: beissert t. BMC Cancer. 2006 Nov 7;6:262. doi: 10.1186/1471-2407-6-262. BMC Cancer. 2006. PMID: 17090304 Free PMC article.

2

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

Beissert T, Puccetti E, Bianchini A, Güller S, Boehrer S, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Beissert T, et al. Blood. 2003 Oct 15;102(8):2985-93. doi: 10.1182/blood-2003-03-0811. Epub 2003 Jun 26. Blood. 2003. PMID: 12829585 Free article.

3

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

Puccetti E, Zheng X, Brambilla D, Seshire A, Beissert T, Boehrer S, Nürnberger H, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: beissert t. Cancer Res. 2005 Jul 15;65(14):6080-8. doi: 10.1158/0008-5472.CAN-04-3631. Cancer Res. 2005. PMID: 16024608

4

The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL.

Mian AA, Schüll M, Zhao Z, Oancea C, Hundertmark A, Beissert T, Ottmann OG, Ruthardt M. Mian AA, et al. Among authors: beissert t. Leukemia. 2009 Sep;23(9):1614-21. doi: 10.1038/leu.2009.69. Epub 2009 Apr 16. Leukemia. 2009. PMID: 19369965

5

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

Puccetti E, Obradovic D, Beissert T, Bianchini A, Washburn B, Chiaradonna F, Boehrer S, Hoelzer D, Ottmann OG, Pelicci PG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: beissert t. Cancer Res. 2002 Dec 1;62(23):7050-8. Cancer Res. 2002. PMID: 12460926

6

Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis.

Puccetti E, Beissert T, Güller S, Li JE, Hoelzer D, Ottmann OG, Ruthardt M. Puccetti E, et al. Among authors: beissert t. Oncogene. 2003 Oct 9;22(44):6900-8. doi: 10.1038/sj.onc.1206747. Oncogene. 2003. PMID: 14534537

7

Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.

Zheng X, Seshire A, Rüster B, Bug G, Beissert T, Puccetti E, Hoelzer D, Henschler R, Ruthardt M. Zheng X, et al. Among authors: beissert t. Haematologica. 2007 Mar;92(3):323-31. doi: 10.3324/haematol.10541. Haematologica. 2007. PMID: 17339181 Free article.

8

Targeting of the N-terminal coiled coil oligomerization interface by a helix-2 peptide inhibits unmutated and imatinib-resistant BCR/ABL.

Beissert T, Hundertmark A, Kaburova V, Travaglini L, Mian AA, Nervi C, Ruthardt M. Beissert T, et al. Int J Cancer. 2008 Jun 15;122(12):2744-52. doi: 10.1002/ijc.23467. Int J Cancer. 2008. PMID: 18366061

9

Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.

Zheng X, Beissert T, Kukoc-Zivojnov N, Puccetti E, Altschmied J, Strolz C, Boehrer S, Gul H, Schneider O, Ottmann OG, Hoelzer D, Henschler R, Ruthardt M. Zheng X, et al. Among authors: beissert t. Blood. 2004 May 1;103(9):3535-43. doi: 10.1182/blood-2003-09-3335. Epub 2004 Jan 22. Blood. 2004. PMID: 14739224 Free article.

10

Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.

Bug G, Gül H, Schwarz K, Pfeifer H, Kampfmann M, Zheng X, Beissert T, Boehrer S, Hoelzer D, Ottmann OG, Ruthardt M. Bug G, et al. Among authors: beissert t. Cancer Res. 2005 Apr 1;65(7):2537-41. doi: 10.1158/0008-5472.CAN-04-3011. Cancer Res. 2005. PMID: 15805245

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