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Pyridodiazepine amines are selective therapeutic agents for helicobacter pylori by suppressing growth through inhibition of glutamate racemase but are predicted to require continuous elevated levels in plasma to achieve clinical efficacy.
de Jonge BL, Kutschke A, Newman JV, Rooney MT, Yang W, Cederberg C. de Jonge BL, et al. Among authors: cederberg c. Antimicrob Agents Chemother. 2015 Apr;59(4):2337-42. doi: 10.1128/AAC.04410-14. Epub 2015 Feb 2. Antimicrob Agents Chemother. 2015. PMID: 25645840 Free PMC article.
69 results