Hauck SI - Search Results

1

New carbon-linked azole oxazolidinones with improved potency and pharmacokinetics.

Hauck SI, Cederberg C, Doucette A, Grosser L, Hales NJ, Poon G, Gravestock MB. Hauck SI, et al. Bioorg Med Chem Lett. 2007 Jan 15;17(2):337-40. doi: 10.1016/j.bmcl.2006.10.063. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17095223

2

Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.

Eakin AE, Green O, Hales N, Walkup GK, Bist S, Singh A, Mullen G, Bryant J, Embrey K, Gao N, Breeze A, Timms D, Andrews B, Uria-Nickelsen M, Demeritt J, Loch JT 3rd, Hull K, Blodgett A, Illingworth RN, Prince B, Boriack-Sjodin PA, Hauck S, MacPherson LJ, Ni H, Sherer B. Eakin AE, et al. Antimicrob Agents Chemother. 2012 Mar;56(3):1240-6. doi: 10.1128/AAC.05485-11. Epub 2011 Dec 19. Antimicrob Agents Chemother. 2012. PMID: 22183167 Free PMC article.

3

Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.

Sherer BA, Hull K, Green O, Basarab G, Hauck S, Hill P, Loch JT 3rd, Mullen G, Bist S, Bryant J, Boriack-Sjodin A, Read J, DeGrace N, Uria-Nickelsen M, Illingworth RN, Eakin AE. Sherer BA, et al. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7416-20. doi: 10.1016/j.bmcl.2011.10.010. Epub 2011 Oct 12. Bioorg Med Chem Lett. 2011. PMID: 22041057

4

Antibacterial Spiropyrimidinetriones with N-Linked Azole Substituents on a Benzisoxazole Scaffold Targeting DNA Gyrase.

Basarab GS, Doig P, Eyermann CJ, Galullo V, Kern G, Kimzey A, Kutschke A, Morningstar M, Schuck V, Vishwanathan K, Zhou F, Gowravaram M, Hauck S. Basarab GS, et al. J Med Chem. 2020 Oct 22;63(20):11882-11901. doi: 10.1021/acs.jmedchem.0c01100. Epub 2020 Oct 2. J Med Chem. 2020. PMID: 32914979

5

Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).

Basarab GS, Hill PJ, Garner CE, Hull K, Green O, Sherer BA, Dangel PB, Manchester JI, Bist S, Hauck S, Zhou F, Uria-Nickelsen M, Illingworth R, Alm R, Rooney M, Eakin AE. Basarab GS, et al. J Med Chem. 2014 Jul 24;57(14):6060-82. doi: 10.1021/jm500462x. Epub 2014 Jul 8. J Med Chem. 2014. PMID: 24959892

6

Synthesis of a tetrahydronaphthyridine spiropyrimidinetrione DNA gyrase inhibiting antibacterial agent--differential substitution at all five carbon atoms of pyridine.

Basarab GS, Galullo V, DeGrace N, Hauck S, Joubran C, Wesolowski SS. Basarab GS, et al. Org Lett. 2014 Dec 19;16(24):6456-9. doi: 10.1021/ol503256h. Epub 2014 Dec 2. Org Lett. 2014. PMID: 25458849

7

Synthesis of a photoaffinity analog of taxol as an approach to identify the taxol binding site on microtubules.

Carboni JM, Farina V, Rao S, Hauck SI, Horwitz SB, Ringel I. Carboni JM, et al. Among authors: hauck si. J Med Chem. 1993 Feb 19;36(4):513-5. doi: 10.1021/jm00056a013. J Med Chem. 1993. PMID: 8097253 No abstract available.

8

High turnover number and rapid, room-temperature amination of chloroarenes using saturated carbene ligands.

Stauffer SR, Lee S, Stambuli JP, Hauck SI, Hartwig JF. Stauffer SR, et al. Among authors: hauck si. Org Lett. 2000 May 18;2(10):1423-6. doi: 10.1021/ol005751k. Org Lett. 2000. PMID: 10814463

9

Room-Temperature Palladium-Catalyzed Amination of Aryl Bromides and Chlorides and Extended Scope of Aromatic C-N Bond Formation with a Commercial Ligand.

Hartwig JF, Kawatsura M, Hauck SI, Shaughnessy KH, Alcazar-Roman LM. Hartwig JF, et al. Among authors: hauck si. J Org Chem. 1999 Jul 23;64(15):5575-5580. doi: 10.1021/jo990408i. J Org Chem. 1999. PMID: 11674624

10

Tertiary building units: synthesis, structure, and porosity of a metal-organic dendrimer framework (MODF-1).

Chae HK, Eddaoudi M, Kim J, Hauck SI, Hartwig JF, O'Keeffe M, Yaghi OM. Chae HK, et al. Among authors: hauck si. J Am Chem Soc. 2001 Nov 21;123(46):11482-3. doi: 10.1021/ja011692+. J Am Chem Soc. 2001. PMID: 11707128 No abstract available.

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