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Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid.
Uchiyama A, Mukai M, Fujiwara Y, Kobayashi S, Kawai N, Murofushi H, Inoue M, Enoki S, Tanaka Y, Niki T, Kobayashi T, Tigyi G, Murakami-Murofushi K. Uchiyama A, et al. Among authors: fujiwara y. Biochim Biophys Acta. 2007 Jan;1771(1):103-12. doi: 10.1016/j.bbalip.2006.10.001. Epub 2006 Oct 14. Biochim Biophys Acta. 2007. PMID: 17123862 Free PMC article.
Biological functions of a novel lipid mediator, cyclic phosphatidic acid.
Murakami-Murofushi K, Uchiyama A, Fujiwara Y, Kobayashi T, Kobayashi S, Mukai M, Murofushi H, Tigyi G. Murakami-Murofushi K, et al. Among authors: fujiwara y. Biochim Biophys Acta. 2002 May 23;1582(1-3):1-7. doi: 10.1016/s1388-1981(02)00131-2. Biochim Biophys Acta. 2002. PMID: 12069804 Review.
Carba analogs of cyclic phosphatidic acid are selective inhibitors of autotaxin and cancer cell invasion and metastasis.
Baker DL, Fujiwara Y, Pigg KR, Tsukahara R, Kobayashi S, Murofushi H, Uchiyama A, Murakami-Murofushi K, Koh E, Bandle RW, Byun HS, Bittman R, Fan D, Murph M, Mills GB, Tigyi G. Baker DL, et al. Among authors: fujiwara y. J Biol Chem. 2006 Aug 11;281(32):22786-93. doi: 10.1074/jbc.M512486200. Epub 2006 Jun 16. J Biol Chem. 2006. PMID: 16782709 Free PMC article.
Lysophospholipid signaling: beyond the EDGs.
Valentine WJ, Fujiwara Y, Tsukahara R, Tigyi G. Valentine WJ, et al. Among authors: fujiwara y. Biochim Biophys Acta. 2008 Mar;1780(3):597-605. doi: 10.1016/j.bbagen.2007.08.008. Epub 2007 Aug 25. Biochim Biophys Acta. 2008. PMID: 17931789 Free PMC article.
Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.
Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD. Gupte R, et al. Among authors: fujiwara y. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7525-8. doi: 10.1016/j.bmcl.2010.09.115. Epub 2010 Oct 8. Bioorg Med Chem Lett. 2010. PMID: 21051230 Free PMC article.
Phospholipase D2-dependent inhibition of the nuclear hormone receptor PPARgamma by cyclic phosphatidic acid.
Tsukahara T, Tsukahara R, Fujiwara Y, Yue J, Cheng Y, Guo H, Bolen A, Zhang C, Balazs L, Re F, Du G, Frohman MA, Baker DL, Parrill AL, Uchiyama A, Kobayashi T, Murakami-Murofushi K, Tigyi G. Tsukahara T, et al. Among authors: fujiwara y. Mol Cell. 2010 Aug 13;39(3):421-32. doi: 10.1016/j.molcel.2010.07.022. Mol Cell. 2010. PMID: 20705243 Free PMC article.
Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis.
Gotoh M, Fujiwara Y, Yue J, Liu J, Lee S, Fells J, Uchiyama A, Murakami-Murofushi K, Kennel S, Wall J, Patil R, Gupte R, Balazs L, Miller DD, Tigyi GJ. Gotoh M, et al. Among authors: fujiwara y. Biochem Soc Trans. 2012 Feb;40(1):31-6. doi: 10.1042/BST20110608. Biochem Soc Trans. 2012. PMID: 22260662 Free PMC article. Review.
Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.
Kiss GN, Lee SC, Fells JI, Liu J, Valentine WJ, Fujiwara Y, Thompson KE, Yates CR, Sümegi B, Tigyi G. Kiss GN, et al. Among authors: fujiwara y. Biochim Biophys Acta. 2013 Jan;1831(1):117-25. doi: 10.1016/j.bbalip.2012.08.020. Biochim Biophys Acta. 2013. PMID: 23127512 Free PMC article.
4,261 results