Bevan C - Search Results

1

Estimation of volume of distribution in humans from high throughput HPLC-based measurements of human serum albumin binding and immobilized artificial membrane partitioning.

Hollósy F, Valkó K, Hersey A, Nunhuck S, Kéri G, Bevan C. Hollósy F, et al. Among authors: bevan c. J Med Chem. 2006 Nov 30;49(24):6958-71. doi: 10.1021/jm050957i. J Med Chem. 2006. PMID: 17125249

2

Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity.

Valko K, Nunhuck S, Bevan C, Abraham MH, Reynolds DP. Valko K, et al. Among authors: bevan c. J Pharm Sci. 2003 Nov;92(11):2236-48. doi: 10.1002/jps.10494. J Pharm Sci. 2003. PMID: 14603509

3

Rapid method for the estimation of octanol/water partition coefficient (log P(oct)) from gradient RP-HPLC retention and a hydrogen bond acidity term (zetaalpha(2)(H)).

Valko K, My Du C, Bevan C, Reynolds DP, Abraham MH. Valko K, et al. Among authors: bevan c. Curr Med Chem. 2001 Jul;8(9):1137-46. doi: 10.2174/0929867013372643. Curr Med Chem. 2001. PMID: 11472245 Review.

4

Rapid-gradient HPLC method for measuring drug interactions with immobilized artificial membrane: comparison with other lipophilicity measures.

Valko K, Du CM, Bevan CD, Reynolds DP, Abraham MH. Valko K, et al. Among authors: bevan cd. J Pharm Sci. 2000 Aug;89(8):1085-96. doi: 10.1002/1520-6017(200008)89:8<1085::aid-jps13>3.0.co;2-n. J Pharm Sci. 2000. PMID: 10906732

5

Chromatographic Hydrophobicity Index by Fast-Gradient RP-HPLC: A High-Throughput Alternative to log P/log D.

Valkó K, Bevan C, Reynolds D. Valkó K, et al. Among authors: bevan c. Anal Chem. 1997 Jun 1;69(11):2022-9. doi: 10.1021/ac961242d. Anal Chem. 1997. PMID: 21639241

6

Unique selectivity of perfluorinated stationary phases with 2,2,2-trifluoroethanol as organic mobile phase modifier.

Valkó K, Espinosa S, Du CM, Bosch E, Rosés M, Bevan C, Abraham MH. Valkó K, et al. Among authors: bevan c. J Chromatogr A. 2001 Nov 9;933(1-2):73-81. doi: 10.1016/s0021-9673(01)01254-7. J Chromatogr A. 2001. PMID: 11758748

7

Immobilized human serum albumin: liquid chromatography/mass spectrometry as a method of determining drug-protein binding.

Tiller PR, Mutton IM, Lane SJ, Bevan CD. Tiller PR, et al. Among authors: bevan cd. Rapid Commun Mass Spectrom. 1995;9(4):261-3. doi: 10.1002/rcm.1290090403. Rapid Commun Mass Spectrom. 1995. PMID: 7756700

8

A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates.

Bevan CD, Lloyd RS. Bevan CD, et al. Anal Chem. 2000 Apr 15;72(8):1781-7. doi: 10.1021/ac9912247. Anal Chem. 2000. PMID: 10784141

9

Characterizing the selectivity of stationary phases and organic modifiers in reversed-phase high-performance liquid chromatographic systems by a general solvation equation using gradient elution.

Du CM, Valko K, Bevan C, Reynolds D, Abraham MH. Du CM, et al. Among authors: bevan c. J Chromatogr Sci. 2000 Nov;38(11):503-11. doi: 10.1093/chromsci/38.11.503. J Chromatogr Sci. 2000. PMID: 11105774

10

High-throughput measurement of pKa values in a mixed-buffer linear pH gradient system.

Box K, Bevan C, Comer J, Hill A, Allen R, Reynolds D. Box K, et al. Among authors: bevan c. Anal Chem. 2003 Feb 15;75(4):883-92. doi: 10.1021/ac020329y. Anal Chem. 2003. PMID: 12622380

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