Qi A - Search Results

1

Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors.

El-Tayeb A, Qi A, Müller CE. El-Tayeb A, et al. Among authors: qi a. J Med Chem. 2006 Nov 30;49(24):7076-87. doi: 10.1021/jm060848j. J Med Chem. 2006. PMID: 17125260

2

Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors.

El-Tayeb A, Qi A, Nicholas RA, Müller CE. El-Tayeb A, et al. Among authors: qi a. J Med Chem. 2011 Apr 28;54(8):2878-90. doi: 10.1021/jm1016297. Epub 2011 Mar 21. J Med Chem. 2011. PMID: 21417463

3

Agonist versus antagonist action of ATP at the P2Y4 receptor is determined by the second extracellular loop.

Herold CL, Qi AD, Harden TK, Nicholas RA. Herold CL, et al. Among authors: qi ad. J Biol Chem. 2004 Mar 19;279(12):11456-64. doi: 10.1074/jbc.M301734200. Epub 2003 Dec 11. J Biol Chem. 2004. PMID: 14670966 Free PMC article.

4

Synthesis and characterization of chiral 6-azaspiro[2.5]octanes as potent and selective antagonists of the M₄ muscarinic acetylcholine receptor.

Bender AM, Carter TR, Spock M, Rodriguez AL, Dickerson JW, Rook JM, Chang S, Qi A, Presley CC, Engers DW, Harp JM, Bridges TM, Niswender CM, Conn PJ, Lindsley CW. Bender AM, et al. Among authors: qi a. Bioorg Med Chem Lett. 2022 Jan 15;56:128479. doi: 10.1016/j.bmcl.2021.128479. Epub 2021 Nov 24. Bioorg Med Chem Lett. 2022. PMID: 34838649

5

The apical targeting signal of the P2Y2 receptor is located in its first extracellular loop.

Qi AD, Wolff SC, Nicholas RA. Qi AD, et al. J Biol Chem. 2005 Aug 12;280(32):29169-75. doi: 10.1074/jbc.M501301200. Epub 2005 May 20. J Biol Chem. 2005. PMID: 15908695 Free article.

6

Is GPR17 a P2Y/leukotriene receptor? examination of uracil nucleotides, nucleotide sugars, and cysteinyl leukotrienes as agonists of GPR17.

Qi AD, Harden TK, Nicholas RA. Qi AD, et al. J Pharmacol Exp Ther. 2013 Oct;347(1):38-46. doi: 10.1124/jpet.113.207647. Epub 2013 Aug 1. J Pharmacol Exp Ther. 2013. PMID: 23908386 Free PMC article.

7

An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2Y11 receptors.

Qi AD, Zambon AC, Insel PA, Nicholas RA. Qi AD, et al. Mol Pharmacol. 2001 Dec;60(6):1375-82. doi: 10.1124/mol.60.6.1375. Mol Pharmacol. 2001. PMID: 11723245

8

Ser352 and Ser354 in the carboxyl terminus of the human P2Y(1) receptor are required for agonist-promoted phosphorylation and internalization in MDCK cells.

Qi AD, Houston-Cohen D, Naruszewicz I, Harden TK, Nicholas RA. Qi AD, et al. Br J Pharmacol. 2011 Mar;162(6):1304-13. doi: 10.1111/j.1476-5381.2010.01135.x. Br J Pharmacol. 2011. PMID: 21108629 Free PMC article.

9

Polarized expression of human P2Y receptors in epithelial cells from kidney, lung, and colon.

Wolff SC, Qi AD, Harden TK, Nicholas RA. Wolff SC, et al. Among authors: qi ad. Am J Physiol Cell Physiol. 2005 Mar;288(3):C624-32. doi: 10.1152/ajpcell.00338.2004. Epub 2004 Nov 3. Am J Physiol Cell Physiol. 2005. PMID: 15525684 Free article.

10

Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.

Magnone M, Basile G, Bruzzese D, Guida L, Signorello MG, Chothi MP, Bruzzone S, Millo E, Qi AD, Nicholas RA, Kassack MU, Leoncini G, Zocchi E. Magnone M, et al. Among authors: qi ad. J Biol Chem. 2008 Sep 5;283(36):24460-8. doi: 10.1074/jbc.M710568200. Epub 2008 Jul 7. J Biol Chem. 2008. PMID: 18606819 Free PMC article.

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