Effect of insulin on cell cycle progression in MCF-7 breast cancer cells. Direct and potentiating influence.
Chappell J, Leitner JW, Solomon S, Golovchenko I, Goalstone ML, Draznin B.
Chappell J, et al.
J Biol Chem. 2001 Oct 12;276(41):38023-8. doi: 10.1074/jbc.M104416200. Epub 2001 Aug 10.
J Biol Chem. 2001.
PMID: 11500498
Free article.
We recently demonstrated that in MCF-7 breast cancer cells, insulin promoted the phosphorylation and activation of geranylgeranyltransferase I (GGTI-I), increased the amounts of geranylgeranylated Rho-A and potentiated the transactivating activity of lysophosphatidic acid (LPA) ( …
We recently demonstrated that in MCF-7 breast cancer cells, insulin promoted the phosphorylation and activation of geranylgeranyltransferase …