Little SE - Search Results

1

Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.

Natrajan R, Reis-Filho JS, Little SE, Messahel B, Brundler MA, Dome JS, Grundy PE, Vujanic GM, Pritchard-Jones K, Jones C. Natrajan R, et al. Among authors: little se. Cancer Res. 2006 Dec 1;66(23):11148-55. doi: 10.1158/0008-5472.CAN-06-1931. Cancer Res. 2006. PMID: 17145858

2

Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour.

Natrajan R, Little SE, Sodha N, Reis-Filho JS, Mackay A, Fenwick K, Ashworth A, Perlman EJ, Dome JS, Grundy PE, Pritchard-Jones K, Jones C. Natrajan R, et al. Among authors: little se. J Pathol. 2007 Jan;211(1):52-9. doi: 10.1002/path.2087. J Pathol. 2007. PMID: 17103382

3

Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in Wilms tumor.

Williams RD, Al-Saadi R, Natrajan R, Mackay A, Chagtai T, Little S, Hing SN, Fenwick K, Ashworth A, Grundy P, Anderson JR, Dome JS, Perlman EJ, Jones C, Pritchard-Jones K. Williams RD, et al. Genes Chromosomes Cancer. 2011 Dec;50(12):982-95. doi: 10.1002/gcc.20907. Epub 2011 Aug 31. Genes Chromosomes Cancer. 2011. PMID: 21882282

4

Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors.

Natrajan R, Little SE, Reis-Filho JS, Hing L, Messahel B, Grundy PE, Dome JS, Schneider T, Vujanic GM, Pritchard-Jones K, Jones C. Natrajan R, et al. Among authors: little se. Clin Cancer Res. 2006 Dec 15;12(24):7284-93. doi: 10.1158/1078-0432.CCR-06-1567. Clin Cancer Res. 2006. PMID: 17189400

5

Multifaceted dysregulation of the epidermal growth factor receptor pathway in clear cell sarcoma of the kidney.

Little SE, Bax DA, Rodriguez-Pinilla M, Natrajan R, Messahel B, Pritchard-Jones K, Vujanic GM, Reis-Filho JS, Jones C. Little SE, et al. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4360-4. doi: 10.1158/1078-0432.CCR-07-0398. Epub 2007 Jul 23. Clin Cancer Res. 2007. PMID: 17646270

6

Frequency and heritability of WT1 mutations in nonsyndromic Wilms' tumor patients: a UK Children's Cancer Study Group Study.

Little SE, Hanks SP, King-Underwood L, Jones C, Rapley EA, Rahman N, Pritchard-Jones K. Little SE, et al. J Clin Oncol. 2004 Oct 15;22(20):4140-6. doi: 10.1200/JCO.2004.02.136. J Clin Oncol. 2004. PMID: 15483024

7

Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.

Little SE, Vuononvirta R, Reis-Filho JS, Natrajan R, Iravani M, Fenwick K, Mackay A, Ashworth A, Pritchard-Jones K, Jones C. Little SE, et al. Genomics. 2006 Feb;87(2):298-306. doi: 10.1016/j.ygeno.2005.09.019. Epub 2005 Nov 2. Genomics. 2006. PMID: 16271290 Free article.

8

EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines.

Bax DA, Gaspar N, Little SE, Marshall L, Perryman L, Regairaz M, Viana-Pereira M, Vuononvirta R, Sharp SY, Reis-Filho JS, Stávale JN, Al-Sarraj S, Reis RM, Vassal G, Pearson AD, Hargrave D, Ellison DW, Workman P, Jones C. Bax DA, et al. Among authors: little se. Clin Cancer Res. 2009 Sep 15;15(18):5753-61. doi: 10.1158/1078-0432.CCR-08-3210. Epub 2009 Sep 8. Clin Cancer Res. 2009. PMID: 19737945

9

A distinct spectrum of copy number aberrations in pediatric high-grade gliomas.

Bax DA, Mackay A, Little SE, Carvalho D, Viana-Pereira M, Tamber N, Grigoriadis AE, Ashworth A, Reis RM, Ellison DW, Al-Sarraj S, Hargrave D, Jones C. Bax DA, et al. Among authors: little se. Clin Cancer Res. 2010 Jul 1;16(13):3368-77. doi: 10.1158/1078-0432.CCR-10-0438. Epub 2010 Jun 22. Clin Cancer Res. 2010. PMID: 20570930 Free PMC article.

10

Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity.

Little SE, Popov S, Jury A, Bax DA, Doey L, Al-Sarraj S, Jurgensmeier JM, Jones C. Little SE, et al. Cancer Res. 2012 Apr 1;72(7):1614-20. doi: 10.1158/0008-5472.CAN-11-4069. Epub 2012 Feb 6. Cancer Res. 2012. PMID: 22311673

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