Geldenhuys WJ - Search Results

1

Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor.

Geldenhuys WJ, Malan SF, Bloomquist JR, Van der Schyf CJ. Geldenhuys WJ, et al. Bioorg Med Chem. 2007 Feb 1;15(3):1525-32. doi: 10.1016/j.bmc.2006.09.060. Epub 2006 Sep 29. Bioorg Med Chem. 2007. PMID: 17157509

2

Screening of novel pentacyclo-undecylamines for neuroprotective activity.

Geldenhuys WJ, Terre'Blanche G, Van der Schyf CJ, Malan SF. Geldenhuys WJ, et al. Eur J Pharmacol. 2003 Jan 1;458(1-2):73-9. doi: 10.1016/s0014-2999(02)02701-2. Eur J Pharmacol. 2003. PMID: 12498909

3

Synthesis and biological evaluation of pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane derivatives as potential therapeutic agents in Parkinson's disease.

Geldenhuys WJ, Malan SF, Murugesan T, Van der Schyf CJ, Bloomquist JR. Geldenhuys WJ, et al. Bioorg Med Chem. 2004 Apr 1;12(7):1799-806. doi: 10.1016/j.bmc.2003.12.045. Bioorg Med Chem. 2004. PMID: 15028270

4

Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter.

Geldenhuys WJ, Lockman PR, McAfee JH, Fitzpatrick KT, Van der Schyf CJ, Allen DD. Geldenhuys WJ, et al. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3085-92. doi: 10.1016/j.bmcl.2004.04.020. Bioorg Med Chem Lett. 2004. PMID: 15149650

5

Pharmacology and structure-activity relationships of bioactive polycyclic cage compounds: a focus on pentacycloundecane derivatives.

Geldenhuys WJ, Malan SF, Bloomquist JR, Marchand AP, Van der Schyf CJ. Geldenhuys WJ, et al. Med Res Rev. 2005 Jan;25(1):21-48. doi: 10.1002/med.20013. Med Res Rev. 2005. PMID: 15389731 Review.

6

Synthesis, biological evaluation, and molecular modeling of novel thioacridone derivatives related to the anticancer alkaloid acronycine.

Dheyongera JP, Geldenhuys WJ, Dekker TG, Van der Schyf CJ. Dheyongera JP, et al. Among authors: geldenhuys wj. Bioorg Med Chem. 2005 Feb 1;13(3):689-98. doi: 10.1016/j.bmc.2004.10.051. Bioorg Med Chem. 2005. PMID: 15653336

7

Antimalarial activity of thioacridone compounds related to the acronycine alkaloid.

Dheyongera JP, Geldenhuys WJ, Dekker TG, Matsabisa MG, Van der Schyf CJ. Dheyongera JP, et al. Among authors: geldenhuys wj. Bioorg Med Chem. 2005 Mar 1;13(5):1653-9. doi: 10.1016/j.bmc.2004.12.009. Bioorg Med Chem. 2005. PMID: 15698783

8

Brain uptake kinetics of nicotine and cotinine after chronic nicotine exposure.

Lockman PR, McAfee G, Geldenhuys WJ, Van der Schyf CJ, Abbruscato TJ, Allen DD. Lockman PR, et al. Among authors: geldenhuys wj. J Pharmacol Exp Ther. 2005 Aug;314(2):636-42. doi: 10.1124/jpet.105.085381. Epub 2005 Apr 21. J Pharmacol Exp Ther. 2005. PMID: 15845856

9

3D-QSAR study of bis-azaaromatic quaternary ammonium analogs at the blood-brain barrier choline transporter.

Geldenhuys WJ, Lockman PR, Nguyen TH, Van der Schyf CJ, Crooks PA, Dwoskin LP, Allen DD. Geldenhuys WJ, et al. Bioorg Med Chem. 2005 Jul 1;13(13):4253-61. doi: 10.1016/j.bmc.2005.04.020. Bioorg Med Chem. 2005. PMID: 15878282

10

NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia.

Mdzinarishvili A, Geldenhuys WJ, Abbruscato TJ, Bickel U, Klein J, Van der Schyf CJ. Mdzinarishvili A, et al. Among authors: geldenhuys wj. Neurosci Lett. 2005 Jul 22-29;383(1-2):49-53. doi: 10.1016/j.neulet.2005.03.042. Epub 2005 Apr 13. Neurosci Lett. 2005. PMID: 15936510

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