Van der Schyf CJ - Search Results

1

Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor.

Geldenhuys WJ, Malan SF, Bloomquist JR, Van der Schyf CJ. Geldenhuys WJ, et al. Among authors: van der schyf cj. Bioorg Med Chem. 2007 Feb 1;15(3):1525-32. doi: 10.1016/j.bmc.2006.09.060. Epub 2006 Sep 29. Bioorg Med Chem. 2007. PMID: 17157509

2

Rationally designed multi-targeted agents against neurodegenerative diseases.

Geldenhuys WJ, Van der Schyf CJ. Geldenhuys WJ, et al. Among authors: van der schyf cj. Curr Med Chem. 2013;20(13):1662-72. doi: 10.2174/09298673113209990112. Curr Med Chem. 2013. PMID: 23410161 Review.

3

Synthesis and biological evaluation of pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane derivatives as potential therapeutic agents in Parkinson's disease.

Geldenhuys WJ, Malan SF, Murugesan T, Van der Schyf CJ, Bloomquist JR. Geldenhuys WJ, et al. Among authors: van der schyf cj. Bioorg Med Chem. 2004 Apr 1;12(7):1799-806. doi: 10.1016/j.bmc.2003.12.045. Bioorg Med Chem. 2004. PMID: 15028270

4

Pharmacology and structure-activity relationships of bioactive polycyclic cage compounds: a focus on pentacycloundecane derivatives.

Geldenhuys WJ, Malan SF, Bloomquist JR, Marchand AP, Van der Schyf CJ. Geldenhuys WJ, et al. Among authors: van der schyf cj. Med Res Rev. 2005 Jan;25(1):21-48. doi: 10.1002/med.20013. Med Res Rev. 2005. PMID: 15389731 Review.

5

Synthesis, biological evaluation, and molecular modeling of novel thioacridone derivatives related to the anticancer alkaloid acronycine.

Dheyongera JP, Geldenhuys WJ, Dekker TG, Van der Schyf CJ. Dheyongera JP, et al. Among authors: van der schyf cj. Bioorg Med Chem. 2005 Feb 1;13(3):689-98. doi: 10.1016/j.bmc.2004.10.051. Bioorg Med Chem. 2005. PMID: 15653336

6

Antimalarial activity of thioacridone compounds related to the acronycine alkaloid.

Dheyongera JP, Geldenhuys WJ, Dekker TG, Matsabisa MG, Van der Schyf CJ. Dheyongera JP, et al. Among authors: van der schyf cj. Bioorg Med Chem. 2005 Mar 1;13(5):1653-9. doi: 10.1016/j.bmc.2004.12.009. Bioorg Med Chem. 2005. PMID: 15698783

7

Effect of polycyclic cage amines on the transmembrane potential of neuronal cells.

Grobler E, Grobler A, Van der Schyf CJ, Malan SF. Grobler E, et al. Among authors: van der schyf cj. Bioorg Med Chem. 2006 Feb 15;14(4):1176-81. doi: 10.1016/j.bmc.2005.09.042. Epub 2005 Oct 24. Bioorg Med Chem. 2006. PMID: 16249094

8

Serotonin 5-HT6 receptor antagonists for the treatment of Alzheimer's disease.

Geldenhuys WJ, Van der Schyf CJ. Geldenhuys WJ, et al. Among authors: van der schyf cj. Curr Top Med Chem. 2008;8(12):1035-48. doi: 10.2174/156802608785161420. Curr Top Med Chem. 2008. PMID: 18691131 Review.

9

The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease.

Geldenhuys WJ, Van der Schyf CJ. Geldenhuys WJ, et al. Among authors: van der schyf cj. Expert Rev Neurother. 2009 Jul;9(7):1073-85. doi: 10.1586/ern.09.51. Expert Rev Neurother. 2009. PMID: 19589055 Review.

10

Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.

Geldenhuys WJ, Darvesh AS, Funk MO, Van der Schyf CJ, Carroll RT. Geldenhuys WJ, et al. Among authors: van der schyf cj. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5295-8. doi: 10.1016/j.bmcl.2010.06.128. Epub 2010 Jul 1. Bioorg Med Chem Lett. 2010. PMID: 20650633

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