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Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor.
Walter DH, Rochwalsky U, Reinhold J, Seeger F, Aicher A, Urbich C, Spyridopoulos I, Chun J, Brinkmann V, Keul P, Levkau B, Zeiher AM, Dimmeler S, Haendeler J. Walter DH, et al. Among authors: chun j. Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):275-82. doi: 10.1161/01.ATV.0000254669.12675.70. Epub 2006 Dec 7. Arterioscler Thromb Vasc Biol. 2007. PMID: 17158356
HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production.
Tölle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR. Tölle M, et al. Among authors: chun j. Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1542-8. doi: 10.1161/ATVBAHA.107.161042. Epub 2008 May 15. Arterioscler Thromb Vasc Biol. 2008. PMID: 18483405 Free PMC article.
High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor.
Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B. Theilmeier G, et al. Among authors: chun j. Circulation. 2006 Sep 26;114(13):1403-9. doi: 10.1161/CIRCULATIONAHA.105.607135. Epub 2006 Sep 18. Circulation. 2006. PMID: 16982942
High-density lipoprotein stimulates myocardial perfusion in vivo.
Levkau B, Hermann S, Theilmeier G, van der Giet M, Chun J, Schober O, Schäfers M. Levkau B, et al. Among authors: chun j. Circulation. 2004 Nov 23;110(21):3355-9. doi: 10.1161/01.CIR.0000147827.43912.AE. Epub 2004 Nov 15. Circulation. 2004. PMID: 15545521
HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.
Nofer JR, van der Giet M, Tölle M, Wolinska I, von Wnuck Lipinski K, Baba HA, Tietge UJ, Gödecke A, Ishii I, Kleuser B, Schäfers M, Fobker M, Zidek W, Assmann G, Chun J, Levkau B. Nofer JR, et al. Among authors: chun j. J Clin Invest. 2004 Feb;113(4):569-81. doi: 10.1172/JCI18004. J Clin Invest. 2004. PMID: 14966566 Free PMC article.
Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning.
Keul P, van Borren MM, Ghanem A, Müller FU, Baartscheer A, Verkerk AO, Stümpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijnse AE, Hermann S, Spijkers LJ, Hiller KH, Herr D, Heusch G, Schäfers M, Peters SL, Chun J, Levkau B. Keul P, et al. Among authors: chun j. J Am Heart Assoc. 2016 May 20;5(5):e003393. doi: 10.1161/JAHA.116.003393. J Am Heart Assoc. 2016. PMID: 27207969 Free PMC article.
Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury.
Herzog C, Schmitz M, Levkau B, Herrgott I, Mersmann J, Larmann J, Johanning K, Winterhalter M, Chun J, Müller FU, Echtermeyer F, Hildebrand R, Theilmeier G. Herzog C, et al. Among authors: chun j. Mediators Inflamm. 2010;2010:425191. doi: 10.1155/2010/425191. Epub 2011 Jan 3. Mediators Inflamm. 2010. PMID: 21274265 Free PMC article.
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.
Keller J, Catala-Lehnen P, Huebner AK, Jeschke A, Heckt T, Lueth A, Krause M, Koehne T, Albers J, Schulze J, Schilling S, Haberland M, Denninger H, Neven M, Hermans-Borgmeyer I, Streichert T, Breer S, Barvencik F, Levkau B, Rathkolb B, Wolf E, Calzada-Wack J, Neff F, Gailus-Durner V, Fuchs H, de Angelis MH, Klutmann S, Tsourdi E, Hofbauer LC, Kleuser B, Chun J, Schinke T, Amling M. Keller J, et al. Among authors: chun j. Nat Commun. 2014 Oct 21;5:5215. doi: 10.1038/ncomms6215. Nat Commun. 2014. PMID: 25333900 Free PMC article.
2,464 results