Radominska-Pandya A - Search Results

1

Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10.

Starlard-Davenport A, Xiong Y, Bratton S, Gallus-Zawada A, Finel M, Radominska-Pandya A. Starlard-Davenport A, et al. Steroids. 2007 Jan;72(1):85-94. doi: 10.1016/j.steroids.2006.11.016. Epub 2006 Dec 15. Steroids. 2007. PMID: 17174996 Free PMC article.

2

Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases.

Little JM, Kurkela M, Sonka J, Jäntti S, Ketola R, Bratton S, Finel M, Radominska-Pandya A. Little JM, et al. J Lipid Res. 2004 Sep;45(9):1694-703. doi: 10.1194/jlr.M400103-JLR200. Epub 2004 Jul 1. J Lipid Res. 2004. PMID: 15231852 Free article.

3

A historical overview of the heterologous expression of mammalian UDP-glucuronosyltransferase isoforms over the past twenty years.

Radominska-Pandya A, Bratton S, Little JM. Radominska-Pandya A, et al. Curr Drug Metab. 2005 Apr;6(2):141-60. doi: 10.2174/1389200053586127. Curr Drug Metab. 2005. PMID: 15853765 Review.

4

Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis.

Xiong Y, Bernardi D, Bratton S, Ward MD, Battaglia E, Finel M, Drake RR, Radominska-Pandya A. Xiong Y, et al. Biochemistry. 2006 Feb 21;45(7):2322-32. doi: 10.1021/bi0519001. Biochemistry. 2006. PMID: 16475821

5

Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.

Zielinska A, Lichti CF, Bratton S, Mitchell NC, Gallus-Zawada A, Le VH, Finel M, Miller GP, Radominska-Pandya A, Moran JH. Zielinska A, et al. J Pharmacol Exp Ther. 2008 Jan;324(1):139-48. doi: 10.1124/jpet.107.129858. Epub 2007 Oct 5. J Pharmacol Exp Ther. 2008. PMID: 17921187 Free PMC article.

6

Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene.

Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Starlard-Davenport A, et al. Steroids. 2008 Jan;73(1):139-47. doi: 10.1016/j.steroids.2007.09.007. Epub 2007 Sep 29. Steroids. 2008. PMID: 17981312 Free PMC article.

7

The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis.

Xiong Y, Patana AS, Miley MJ, Zielinska AK, Bratton SM, Miller GP, Goldman A, Finel M, Redinbo MR, Radominska-Pandya A. Xiong Y, et al. Drug Metab Dispos. 2008 Mar;36(3):517-22. doi: 10.1124/dmd.107.016469. Epub 2007 Nov 29. Drug Metab Dispos. 2008. PMID: 18048489 Free PMC article.

8

Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues.

Starlard-Davenport A, Lyn-Cook B, Radominska-Pandya A. Starlard-Davenport A, et al. Steroids. 2008 Jul;73(6):611-20. doi: 10.1016/j.steroids.2008.01.019. Epub 2008 Feb 3. Steroids. 2008. PMID: 18374377 Free PMC article.

9

Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin.

Miller GP, Lichti CF, Zielinska AK, Mazur A, Bratton SM, Gallus-Zawada A, Finel M, Moran JH, Radominska-Pandya A. Miller GP, et al. Drug Metab Dispos. 2008 Nov;36(11):2211-8. doi: 10.1124/dmd.108.022863. Epub 2008 Aug 25. Drug Metab Dispos. 2008. PMID: 18725508 Free PMC article.

10

Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids.

Mazur A, Lichti CF, Prather PL, Zielinska AK, Bratton SM, Gallus-Zawada A, Finel M, Miller GP, Radomińska-Pandya A, Moran JH. Mazur A, et al. Drug Metab Dispos. 2009 Jul;37(7):1496-504. doi: 10.1124/dmd.109.026898. Epub 2009 Apr 1. Drug Metab Dispos. 2009. PMID: 19339377 Free PMC article.

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