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In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the release of beta interferon.
Mangino G, Percario ZA, Fiorucci G, Vaccari G, Manrique S, Romeo G, Federico M, Geyer M, Affabris E. Mangino G, et al. Among authors: romeo g. J Virol. 2007 Mar;81(6):2777-91. doi: 10.1128/JVI.01640-06. Epub 2006 Dec 20. J Virol. 2007. PMID: 17182689 Free PMC article.
Spectrum of biological activity of interferons.
Battistini A, Affabris E, Fiorucci G, Coccia EM, Romeo G, Marziali G, Rossi GB. Battistini A, et al. Among authors: romeo g. Ann Ist Super Sanita. 1990;26(3-4):227-53. Ann Ist Super Sanita. 1990. PMID: 1708952 Review.
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