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Chitosan immunomodulation: insights into mechanisms of action on immune cells and signaling pathways.
Ghattas M, Dwivedi G, Chevrier A, Horn-Bourque D, Alameh MG, Lavertu M. Ghattas M, et al. RSC Adv. 2025 Jan 10;15(2):896-909. doi: 10.1039/d4ra08406c. eCollection 2025 Jan 9. RSC Adv. 2025. PMID: 39802469 Free PMC article. Review.
Chitosan, a biodegradable and biocompatible natural polymer composed of beta-(1-4)-linked N-acetyl glucosamine (GlcNAc) and d-glucosamine (GlcN) and derived from crustacean shells, has been widely studied for various biomedical applications, including drug delivery, …
Chitosan, a biodegradable and biocompatible natural polymer composed of beta-(1-4)-linked N-acetyl glucosamine (GlcNAc) and d-gluc …
Complex transcription regulation of acidic chitinase suggests fine-tuning of digestive processes in Drosera binata.
Mikitova V, Jopcik M, Rajninec M, Libantova J. Mikitova V, et al. Planta. 2025 Jan 12;261(2):32. doi: 10.1007/s00425-025-04607-2. Planta. 2025. PMID: 39799526
The recombinant protein did not cleave chitin powder, the mono-, di- and tri- N-acetyl-D-glucosamine substrates, but cleaved acetic acid-swollen chitin. Fluorometric assay with acetic acid-swollen FITC-chitin as a substrate revealed the maximum enzyme activity at pH 2.5, s …
The recombinant protein did not cleave chitin powder, the mono-, di- and tri- N-acetyl-D-glucosamine substrates, but cleaved acetic a …
Association of Mucin-Degrading Gut Microbiota and Dietary Patterns with Colonic Transit Time in Constipation: A Secondary Analysis of a Randomized Clinical Trial.
Wu X, Yang HJ, Ryu MS, Jung SJ, Ha K, Jeong DY, Park S. Wu X, et al. Nutrients. 2024 Dec 31;17(1):138. doi: 10.3390/nu17010138. Nutrients. 2024. PMID: 39796573 Free PMC article. Clinical Trial.
Metabolic modeling predicted increased N-acetyl-D-glucosamine (GlcNAc), a mucin-derived metabolite, in the slow-transit group. Network analysis identified two microbial co-abundance groups (CAG3 and CAG9) significantly associated with transit time and dietary patterns. ...
Metabolic modeling predicted increased N-acetyl-D-glucosamine (GlcNAc), a mucin-derived metabolite, in the slow-transit group. Networ …
Long-term glucosamine supplementation aggravates atrial fibrillation susceptibility by impairing AMPK signaling.
Qin X, Gong H, Jin L, Wang Y, Dang K, Li H, Zheng Q. Qin X, et al. Life Sci. 2025 Jan 7;362:123380. doi: 10.1016/j.lfs.2025.123380. Online ahead of print. Life Sci. 2025. PMID: 39788416
This study aimed to investigate the effects of long-term glucosamine supplementation on AF susceptibility and the underlying mechanisms. MATERIALS AND METHODS: C57BL/6 J mice were treated with low-dose (15 mg/kg/day) or high-dose (250 mg/kg/day) glucosamine via drin …
This study aimed to investigate the effects of long-term glucosamine supplementation on AF susceptibility and the underlying mechanis …
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