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Role of the WNK-activated SPAK kinase in regulating blood pressure.
Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR. Rafiqi FH, et al. EMBO Mol Med. 2010 Feb;2(2):63-75. doi: 10.1002/emmm.200900058. EMBO Mol Med. 2010. PMID: 20091762 Free PMC article.
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.
San-Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G. San-Cristobal P, et al. Among authors: rafiqi fh. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4384-9. doi: 10.1073/pnas.0813238106. Epub 2009 Feb 24. Proc Natl Acad Sci U S A. 2009. PMID: 19240212 Free PMC article.