Walsh CT - Search Results

1

A singular enzymatic megacomplex from Bacillus subtilis.

Straight PD, Fischbach MA, Walsh CT, Rudner DZ, Kolter R. Straight PD, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):305-10. doi: 10.1073/pnas.0609073103. Epub 2006 Dec 26. Proc Natl Acad Sci U S A. 2007. PMID: 17190806 Free PMC article.

2

In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase.

Fischbach MA, Lin H, Liu DR, Walsh CT. Fischbach MA, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):571-6. doi: 10.1073/pnas.0408463102. Epub 2004 Dec 14. Proc Natl Acad Sci U S A. 2005. PMID: 15598734 Free PMC article.

3

Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase.

Yin J, Straight PD, McLoughlin SM, Zhou Z, Lin AJ, Golan DE, Kelleher NL, Kolter R, Walsh CT. Yin J, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15815-20. doi: 10.1073/pnas.0507705102. Epub 2005 Oct 19. Proc Natl Acad Sci U S A. 2005. PMID: 16236721 Free PMC article.

4

A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection.

Lai JR, Fischbach MA, Liu DR, Walsh CT. Lai JR, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5314-9. doi: 10.1073/pnas.0601038103. Epub 2006 Mar 27. Proc Natl Acad Sci U S A. 2006. PMID: 16567620 Free PMC article.

5

The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis.

Butcher RA, Schroeder FC, Fischbach MA, Straight PD, Kolter R, Walsh CT, Clardy J. Butcher RA, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1506-9. doi: 10.1073/pnas.0610503104. Epub 2007 Jan 18. Proc Natl Acad Sci U S A. 2007. PMID: 17234808 Free PMC article.

6

Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display.

Yin J, Straight PD, Hrvatin S, Dorrestein PC, Bumpus SB, Jao C, Kelleher NL, Kolter R, Walsh CT. Yin J, et al. Among authors: walsh ct. Chem Biol. 2007 Mar;14(3):303-12. doi: 10.1016/j.chembiol.2007.01.006. Chem Biol. 2007. PMID: 17379145

7

Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes.

Fischbach MA, Lai JR, Roche ED, Walsh CT, Liu DR. Fischbach MA, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11951-6. doi: 10.1073/pnas.0705348104. Epub 2007 Jul 9. Proc Natl Acad Sci U S A. 2007. PMID: 17620609 Free PMC article.

8

The evolution of gene collectives: How natural selection drives chemical innovation.

Fischbach MA, Walsh CT, Clardy J. Fischbach MA, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4601-8. doi: 10.1073/pnas.0709132105. Epub 2008 Jan 23. Proc Natl Acad Sci U S A. 2008. PMID: 18216259 Free PMC article.

9

Repurposing libraries of eukaryotic protein kinase inhibitors for antibiotic discovery.

Walsh CT, Fischbach MA. Walsh CT, et al. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1689-90. doi: 10.1073/pnas.0813405106. Epub 2009 Feb 4. Proc Natl Acad Sci U S A. 2009. PMID: 19193851 Free PMC article. Review. No abstract available.

10

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.

Wieland Brown LC, Acker MG, Clardy J, Walsh CT, Fischbach MA. Wieland Brown LC, et al. Among authors: walsh ct. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2549-53. doi: 10.1073/pnas.0900008106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196969 Free PMC article.

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