Fry AM - Search Results

1

Structure and regulation of the human Nek2 centrosomal kinase.

Rellos P, Ivins FJ, Baxter JE, Pike A, Nott TJ, Parkinson DM, Das S, Howell S, Fedorov O, Shen QY, Fry AM, Knapp S, Smerdon SJ. Rellos P, et al. Among authors: fry am. J Biol Chem. 2007 Mar 2;282(9):6833-42. doi: 10.1074/jbc.M609721200. Epub 2006 Dec 31. J Biol Chem. 2007. PMID: 17197699 Free article.

2

Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase.

Wu W, Baxter JE, Wattam SL, Hayward DG, Fardilha M, Knebel A, Ford EM, da Cruz e Silva EF, Fry AM. Wu W, et al. Among authors: fry am. J Biol Chem. 2007 Sep 7;282(36):26431-40. doi: 10.1074/jbc.M704969200. Epub 2007 Jul 11. J Biol Chem. 2007. PMID: 17626005 Free article.

3

An undecided coiled coil: the leucine zipper of Nek2 kinase exhibits atypical conformational exchange dynamics.

Croasdale R, Ivins FJ, Muskett F, Daviter T, Scott DJ, Hardy T, Smerdon SJ, Fry AM, Pfuhl M. Croasdale R, et al. Among authors: fry am. J Biol Chem. 2011 Aug 5;286(31):27537-47. doi: 10.1074/jbc.M110.196972. Epub 2011 Jun 13. J Biol Chem. 2011. PMID: 21669869 Free PMC article.

4

Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases.

Rapley J, Baxter JE, Blot J, Wattam SL, Casenghi M, Meraldi P, Nigg EA, Fry AM. Rapley J, et al. Among authors: fry am. Mol Cell Biol. 2005 Feb;25(4):1309-24. doi: 10.1128/MCB.25.4.1309-1324.2005. Mol Cell Biol. 2005. PMID: 15684383 Free PMC article.

5

Sealed with a Kiz: How Plk1 ensures spindle pole integrity.

Fry AM, Baxter JE. Fry AM, et al. Dev Cell. 2006 Oct;11(4):431-2. doi: 10.1016/j.devcel.2006.09.012. Dev Cell. 2006. PMID: 17011480 Free article.

6

Insights into the conformational variability and regulation of human Nek2 kinase.

Westwood I, Cheary DM, Baxter JE, Richards MW, van Montfort RL, Fry AM, Bayliss R. Westwood I, et al. Among authors: fry am. J Mol Biol. 2009 Feb 20;386(2):476-85. doi: 10.1016/j.jmb.2008.12.033. Epub 2008 Dec 24. J Mol Biol. 2009. PMID: 19124027 Free PMC article.

7

Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity.

Innocenti P, Cheung KM, Solanki S, Mas-Droux C, Rowan F, Yeoh S, Boxall K, Westlake M, Pickard L, Hardy T, Baxter JE, Aherne GW, Bayliss R, Fry AM, Hoelder S. Innocenti P, et al. Among authors: fry am. J Med Chem. 2012 Apr 12;55(7):3228-41. doi: 10.1021/jm201683b. Epub 2012 Mar 23. J Med Chem. 2012. PMID: 22404346 Free PMC article.

8

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction.

Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E. Mardin BR, et al. Among authors: fry am. Nat Cell Biol. 2010 Dec;12(12):1166-76. doi: 10.1038/ncb2120. Epub 2010 Nov 14. Nat Cell Biol. 2010. PMID: 21076410 Free PMC article.

9

Casein kinase II stabilizes the activity of human topoisomerase IIalpha in a phosphorylation-independent manner.

Redwood C, Davies SL, Wells NJ, Fry AM, Hickson ID. Redwood C, et al. Among authors: fry am. J Biol Chem. 1998 Feb 6;273(6):3635-42. doi: 10.1074/jbc.273.6.3635. J Biol Chem. 1998. PMID: 9452492 Free article.

10

Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif.

Fry AM, Arnaud L, Nigg EA. Fry AM, et al. J Biol Chem. 1999 Jun 4;274(23):16304-10. doi: 10.1074/jbc.274.23.16304. J Biol Chem. 1999. PMID: 10347187 Free article.

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